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Ch 13 Biol 104

Molecular Basis of Inheritance

TermDefinition
Transformation Change in genotype or phenotype due to the assimilation of external DNA by a cell
Griffith’s Experiment An experiment with mice that show that living non-pathogenic bacteria could be transformed into pathogenic bacteria by a heritable substance from dead cells
Hershey & Chase Experiment Use radioactive labeled sulfur and phosphorus to show that the transforming substance was the part of the bacteriophage inside of the protein coat, not the coat itself
Chargaff Experiment Showed that A=T and C=G when analyzing the genetic material of any given species.
The DNA backbone alternating sugars and phosphates of linked nucleotides
Franklin’s Experiment X-Ray crystallography data showed genetic material to be helical, and provided the width of the helix
Watson and Crick Experiment combined data from many other scientists to determine the double helix structure of DNA
Meselson and Stahl Experiment Experiment that proved DNA replication is semi conservative
Created by: PRO Teacher etucci
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