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N126-MH-Depression
Dobrisky-Mental Health-drugs used for depression
| Question | Answer |
|---|---|
| What are the three neurotransmitters associated with depression? | dopamine, norepinephrine and serotonin. |
| What are the 4 categories of meds used in depression? | TCAs, MAOIs, SSRIs, other |
| TCAs cause lots of side effects, which is the most prelevant? | anticholinergic side effects |
| TCAs are contraindicated in patients with seizure disorders because of it's action to | reduce seizure thresholds |
| Name two TCAs | Elavil & Pamelor |
| What two neurotransmitters are affected by TCAs and how? | serotonin and norepinephrine, both increased |
| Which category is 1st generation antidepressants? | TCAs |
| Which category of antidepressants stops the movement of serotonin out of the synapse to allow the brain more use of it? | SSRIs |
| Elavil is a | TCA |
| Pamelor is a | TCA |
| Celexa is a | SSRI |
| Paxil is a | SSRI |
| Zoloft is a | SSRI |
| Lexapro is a | SSRI |
| Nardil is a | MAOI |
| This condition is caused by taking two SSRIs simultaneously | serotonin syndrome |
| The signs and symptoms of Serotonin syndrome are | mental status changes, labile BP and hyper-reflexia |
| The three main side effects of SSRIs are | decreased sex drive, headache, insomnia |
| The use of MAOIs require patient teaching in what important area? | avoidance of tyramine in the diet |
| What causes hypertensive crisis? | when patient taking MAOI ingests tyramine |
| What are the signs and symptoms of hypertensive crisis? | high BP, severe ocipital headache and chest pain |
| How do MAOIs affect neurotransmitters? | increase both serotonin and norepinephrine |
| What is the main action of MAOIs? | inhibits enzymes from metabolizing serotonine and norepinephrine |
| Because of their many side effects these two categories of anti-depressants are not used very often. | TCAs and MAOIs |
| Wellbutrin, Effexor, Rimeron, Cymbalta, Trazadone & Desyrl are all considered to be in what category of depression meds? | other |
| Effexor, Rimeron & Cymbalta cause what two common side effects? | anticholinergic and strange dreams |
| These two "other" antidepressants cause dry mouth, drowsiness and n/v | Trazadone and Desyrl |
| Which antidepressant causes a loss in weight? | Wellbutrin |
| Wellbutrin is known for not causing these two common sidefeccts | weight gain and decreased sex drive |
| What is the "category" for the first group of antidepressants ever used? | TCAs |
| Because of lower side effects these antidepressants are used more often than others | SSRIs |
| When you hear "can't see, can't spit, can't pee" what type of side effect is that? | anticholinergic |