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Chapter 16
Vocabulary Terms
| Term | Definition |
|---|---|
| Erwin Chargaff's Rule | 1. DNA composition varies between organisms 2. In any species, the amount of A=T, and the amount of G=C |
| Antiparallel | DNA subunits run in opposite directions. 5-3, 3-5 |
| DNA replication | Process where DNA is copied and cells can repair DNA |
| Transformation | The change in genotype and phenotype due to foreign DNA |
| Virus | DNA(sometimes RNA) enclosed by a protective coat that is usually simply protein. |
| Semiconservative Model | Predicts when a double helix replicates, each daughter molecule will have 1 old strand and 1 new strand. |
| DNA polymerase | catalyzes elongation of new DNA at replication fork |
| dATP | Supplies adenine to DNA |
| Leading strand | Synthesized by DNA polymerase continuously and moves toward replication fork. |
| Lagging strand | Elongated by DNA polymerase. Works in the opposite direction from the replication fork. |
| Okazaki Fragments | What a lagging strand is synthesized into |
| DNA ligase | Joins okazaki Fragments |
| Mismatch repair | repair enzymes correct base pairing errors |
| nucleotide excision repair | nuclease cuts out and replaces damaged stretches of DNA |
| telomeres | nucleotide sequences at the ends of eukaryotic chromosomal DNA |
| Telomerase | enzyme that catalyzes the lengthening of telomeres in germ cells |
| bacterial chromosome | double stranded circular DNA molecule associated with a small amount of protein |
| Eukaryotic chromosome | Linear DNA molecule associated with a large amount of protein. |
| Nucleoid | Region of cell where DNA is supercoiled. (bacteria) |
| Chromatin | mixture of DNA and protein that forms chromosomes |
| euchromatin | Loosely packed chromatin |
| Heterochromatin | Highly condensed chromatin during interphase. |
| HIstones | Undergo chemical modifications that changes chromatin organization. |