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CCC Intracranial Inf

CCC Pediatric Intracranial Infections

Bacterial Meningitis acute inflammation of the meninges and CSF
Prevention of decreased incidences of Bacterial Meningitis. Hib vaccination
Aseptic Meningitis caused by many different values
Most common route of infection for Bacterial Meningitis vascular dissemination from a focus infection elsewhere
Where do infections of bacterial meningitis extend to? Ventricles; thick pus, fibrin or adhesions may occlude and obstruct CSF
Onset of Bacterial Meningitis abrupt: fever, chills, headache, vomiting followed by alterations in sensorium
Diagnostic test for bacterial meningitis Lumbar puncture and blood culture
Therapeutic management of bacterial meningitis isolations precautions; initiation of antimicrobial therapy; maintain hydration, ventilation; reduction of intracranial pressure; control seizures & temp; manage systemic shock
Drug of choice for bacterial meningitis antibiotic chosen according to sensitivity to bacteria
Percent of cases of Bacterial meningitis that are fatal 15% of cases are fatal
Aseptic Bacterial Meningitis onset abrupt or gradual, s/s appear 1-2 days after onset
Encephalitis inflammatory prcess of CNS caused by organisms (bacteria, spirochetes, fungi, protozoa, helminths, virus)
Etiology of encephalitis direct invasion of the CNS by virus, post infections involvement of CNS after viral disease; most cases associated with childhood viral disease, other cases associated with mosquitoes and ticks
Diagnosis of encephalitis mild to severe; cann resolve spontaneously or be severe (CNS damage; based on clinical findings
Reye's Syndrome toxic encephalopathy associate with other characteristic organ involvement. Develop fever, impaired consciousness, disordered hepatic function
Etiology of Reye's syndrome Not known. may follow a viral illness like the flu or chickenpox; associated with aspirin use during sickness
Pathophysiology of Reye's syndrome cerebral edema and fatty changes to the liver
Mortality rate of Reye's syndrome 40% mortality rate; if a child recovers, it is rapid and complete but may have lasting effects
Diagnotic lab for Reye's syndrome liver biopsy
Six stage therapeutic criteria for Reye's syndrome Stage I: maintain proper glucose level, pH, electrolyte levelsStage II-VI: prevent/decrease cerebral edema, intubate/deliberately hyperventilate; deliberately paralyze child and sedate to minimize anxiey; parateneal dialysis
Created by: RJost