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PC_Antifungals
Pharmacology
| Question | Answer |
|---|---|
| MOA | Prevent synthesis of ergosterol and hibit fungal cytochrome P-450 |
| AR | Liver toxicities may develop, therefore liver function tests are recommended. gastrointestinal distress may occur. Photosensitivity, rashes, and nausea. |
| SC | May be used as either topical or systemic agent. Pulse dosing is recommended for nail fungal infections. Consuming a cola before taking itraconazole is recommended. Fatty meals should be taken with griseofulvin. |
| SC continuted | Fluconazole suspension should be refrigerated and will expire in 14 days. |