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PC_Aminoglycosides
Pharmacology
Question | Answer |
---|---|
MOA | Inhibit bacterial protein synthesis by bnding to ribosomal subunits |
CI | Life-threatening infections, sepsis, immunocompromised patients |
AR | Nephrotoxicity, ototoxicity, tinnitus, permanent deafness |
SC | Doasges need to be adjusted for each patient after first dose. Once per day dosing has tendency to reduce toxicities. |