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Unite 3 Topic 1-4
Cell Communication, Signal Transduction
| Question | Answer |
|---|---|
| Direct Contact | Communication through cell junctions |
| Gap Junction | Animal Cell |
| Plasmodesmata | Plant Cell |
| Hormones | Sending signals into the bloodstream and tissues. |
| Reception | The detection and receiving of a ligand by a receptor in the target cell |
| Transduction | conversion of extracellular signal to an intercellular signal that will bring about a cellular response. |
| Receptor | Accepts ligand into the cell Can be in: plasma membrane(large or polar) or intracellular(pass through plasma membrane, found in cytoplasm or nucleus) |
| Ligand | Single molecule |
| Second Messenger | Small, non-protein molecules and ions help relay the message(brodcast) and amplify(more) the response |
| GPCR | G protein coupled receptors |
| Ligand-gated ion channel | When ligand binds to the receptor(gate) opens or closes allowing the diffusion of specific ions to pass.(lead to a cellular respons) |
| Protein Kinase | Adding phosphate to the enzyme |
| Protein Phosphate | Dephosphorylation(remove p) by the enzyme |
| cAMP | Common Second Messenger |
| Response | Final molecule in the signaling pathway converts to a response that will alter(change) a cellular process |
| Signaling Substances | dissolved in the cytoplasm can pass freely between adjacent cell |
| Local Regulators | A secreting cell will release chemical messages(local regulator/ligands) that travel a short distance through the extracellular fluid |
| Chemical messages | Cause response in a target cell |
| Paracrine Signaling | Growth factors |
| Synaptic Signaling | Neurons secrete neurotransmitters |
| Long Distance Signaling | Uses hormones for long distance signaling |
| Long Distance Signaling(Plant) | Release hormones that travel in the plant vascular tissue or through the air to reach target tissues. |
| Long Distance Signaling (Animal) | Uses endocrine signaling(exit). Specialized cells release hormones into the circulatory system where they reach target cells. |
| Signal Transduction Pathway | regulates protein activity through protein kinase and Protein phosphate. |