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Chapter 11
Vocabulary Pt.2
| Term | Definition |
|---|---|
| protein phosphorylation and dephosphoralation | widespread mechanism for regulating protein activity |
| protein kinases | transfers phosphate from ATP to protein |
| Phosphorylation | the process of changing phosphate in ATP to protein |
| signal transduction | multi-step process that greatly amplifies a signal |
| phosphorylation cascade | formed when many relay molecules in signal transduction are protein kinases |
| protein phohotases | quickly move phosphates from proteins |
| dephosphorylation | the process in which phosphates are rapidly removed from proteins |
| second messenger | small, nonprotein, water-soluble molecule or ion that spreads throughout a cell by diffusion |
| Cyclic AMP (cAMP) | one of the most widely used 2nd messengers, releases large amount of salt in the intestines |
| Adenylyl cyclase | enzyme in the membrane that converts ATP to cAMP in response to extracellular signals |
| vibrio cholerae | bacterium that produces a toxin that changes g-protein so it is stuck in its active form |
| output response | cell's response to an extracellular signal |
| signal amplification | enzyme cascades amplify cell's response to signal |
| specificity of cell signaling | different cells have different groups of proteins, which allow cells to detect and respond to different signals |
| signaling efficiency | scaffolding proteins and signaling complexes |
| scaffolding proteins | large relay proteins that other relay proteins are attached to |
| termination of signal | inactivation mechanisms of cell signaling |
| Apoptosis | programmed cell death |