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Bio Ch. 9
What Genes Are
| Term | Definition |
|---|---|
| DNA | the genetic material that transfers information from parents to offspring |
| RNA | single-stranded nucleic acid transcribed from DNA |
| nucleotide | basic repeating subunit of DNA, composed of the sugar deoxyribose, a phosphate group, and one of four bases (A,C,G,T)) |
| base | the nitrogen-containing component of nucleotides |
| base pair | two nucleotides held together by hydrogen bonds between their bases |
| double helix | what DNA is made of |
| base-pairing rules | Adenine pairs with Thymine & Cytosine only pairs with Guanine |
| complementary base-pairing | allows the original strands to serve as “template strands” on which new strands can be built |
| CRISPR | RNA sequence that guides molecular machinery to a DNA sequence through complementary base-pairing |
| histone protein | one of a class of specific proteins that, together with DNA, form nucleosomes |
| nucleosome | “beads” made from short lengths of double stranded DNA wound around histone proteins |
| chromatin fiber | a chromosome in relaxed form, made up of DNA and nucleosomes |
| DNA replication | the duplication of a DNA molecule |
| origin of replication | a DNA sequence where DNA replication is initiated |
| DNA polymerase | the enzyme that builds new strands of DNA in DNA replication |
| primer | a short chain of nucleotides |
| semiconservative replication | each new DNA double helix contains one old strand & one new strand |
| polymerase chain reaction (PCR) | a technique that can produce millions of copies of a DNA sequence in just a few hours |
| mutation | a change to the sequence of nucleotides in an organism’s DNA |
| point mutation | the change of one nucleotide in a single base pair |
| substitution | one nucleotide is substituted for another in a DNA sequence |
| insertion | one nucleotide is added to a DNA sequence |
| deletion | one nucleotides is deleted from a DNA sequence |
| noncoding DNA | DNA that does not code for any kind of functional RNA |
| chromosomal abnormality | the addition or deletion of 1 or more whole chromosomes |