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243 CH 26
243 EXAM 3
Term | Definition |
---|---|
systolic pressure | highest pressure, contraction |
diastolic pressure | low pressure, relax and fill |
mean arterial pressure | average pressure in arterial system during contraction and relaxation |
physical factors influencing blood pressure | blood volume, elastic properties of blood vessels |
physiologic influences of blood pressure | cardiac output, systemic vascular resistance |
systemic vascular resistance | influenced by ability of blood vessels to constrict and dilate |
determinants of CO | heart rate, contractility, preload and afterload |
afterload | ejection of blood from ventricle |
increased afterload | decrease stroke volume |
short term BP regulation | neural mechanisms (SNS), humoral (hormone) mechanisms |
long term BP regulation | renal mechanisms |
paracrine mediators | nitric oxide helps vessels relax and dilate |
baroreceptors | sense volume and pressure, signal SNS |
primary hypertension | increased SNS activity, increased sodium, excess alcohol |
heredity hypertension - primary | genetic factors, environmental, demographic |
water and sodium retention | high sodium intake activates pressor mechanisms and causes water retention |
altered renin aldosterone mechanism | contribute to maintenance and development of hypertension |
stress and increased SNS activity | increases vasoconstriction, increased HR, increased renin release |
secondary hypertension | elevation due to another disorder, ie kidney disease |
contributing factors to hypertension | coarctation of aorta, renal disease, endocrine and neurological disorder, hyperthyroidism, polycythemia, sleep apnea, Cushing syndrome |
pheochromocytoma | tumor on adrenal gland |
malignant hypertension | accelerated form of hypertension, rupture/ stroke complications |
hypertension clinical manifestations | asymptomatic until severe and target organ disease occurs, palpitations, angina, dizziness, fatigue, dyspnea, headache |
hypertension heart damage | left ventricular hypertrophy |
hypertension brain damage | dementia and cognitive impairment |
hypertension peripheral vascular | atherosclerosis, pressure pushes on vessels, inner endothelial is damaged; buildup of plaque, vessels can not constrict/ dilate |
hypertension kidney damage | nephrosclerosis |
hypertensive heart disease | coronary artery disease, left ventricular hypertrophy, heart failure |
blood pressure readings | highest early in morning, lowest at night |
hypertension older adults | lowest rates of BP control, over age of 65 |
hypertension minorities | non hispanic black significantly high |
socioeconomic factors contributing to hypertension | substandard insurance, poor access to healthcare |
pregnancy induced hypertension | toxemia of pregnancy, preeclampsia - young age, first pregnancy, multiple fetuses, diabetic |
manifestations of pregnancy hypertension | proteinuria, edema, sudden weight gain, vision change, nausea |
eclampsia | seizure |
HELLP syndrome | risk for hemolysis, elevated liver enzymes, DIC |
hypertension in children | kidney abnormalities, coarctation of aorta, pheochromocytoma and adrenal cortical disorders |
infants and hypertension | umbilical catheterization and renal artery obstruction caused by thrombosis |
orthostatic hypotension | decrease in blood pressure when standing |
causes of orthostatic hypotension | decrease in venous return to the heart due to lower extremity pooling, response to decreased CO |
condition that decreases vascular volume | dehydration |
conditions that impair muscle pump function | bed rest, spinal injury |
conditions that interfere with cardiovascular reflexes | medications, ANS disorders, baroreflex function |
hypovolemia | excessive use of diuretics, diaphoresis, loss of GI fluid through vomitting and diarrhea |
hypovolemia manifestations | dizziness, visual changes, head and neck discomfort, poor concentration, tremor, presyncope and syncope |
syncope | fainting, loss of consciousness |