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Mycology

FA mycology

QuestionAnswer
What is the endemic location for Histoplasmosis? Mississippi and Ohio River Valleys
What are the pathologic features of Histoplasmosis? Macrophage filled with Histoplasma
What are the unique features of Histoplasmosis? 1. Palatal/tongue ulcers 2. Splenomegaly 3. Pancytopenia 4. Erythema nodosum
Which systemic mycoses is associated with bird or bat droppings and caves? Histoplasmosis
All systemic mycoses: Dimorphic fungus - 20 C --> mold (cold) 37 C --> yeast (hot)
What is the treatment for all systemic mycoses? Local infections --> Fluconazole or Itraconazole Disseminated infection --> Amphotericin B
What is the endemic location for Blastomycosis? Eastern and Central US, Great Lakes
What are the pathologic findings of Blastomycosis? Single Broad-based budding of Blastomyces (same size as RBC)
What are unique signs/symptoms of Blastomycosis? 1. Inflammatory lung disease 2. Disseminate to bone and skin
What is the endemic location for Coccidiodomycosis? Southwestern US, California
What is the pathologic description of Coccidioidomycosis? Spherule (larger than RBC) filled with endospores of Coccidioides
What are unique features of Coccidioidomycosis? Disseminate to skin and bone Erythema nodosum (dessert bumps) Arthralgias (desert rheumatism) +/- meningitis
Which systemic mycosis is associated with dust exposure? Coccidioidomycosis
What is the endemic location of Paracoccidioidomycosis? Latin America
What is the pathologic feature of Paracoccidioidomycosis? Budding yeast with "captain's wheel" formation
Created by: rakomi
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