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Chemo Drugs
Shawnee ADNR193 Chemo Drugs
| Question | Answer |
|---|---|
| Alkylating agents | damage DNA cause break in double-strand helix |
| Antimetabolites | interfere w/ synthesis of DNA, mimic certain essential cellular metabolites the cell incorporates into synthesis of DNA |
| Antitumor antibiotics | modify function of DNA & interfere w/ transcription of RNA |
| Plant alkaloids | interrupt cellular replication in mitosis at metaphase |
| Nitrosurea | like alkylating agents & block specific enzymes |
| Corticosteroids | disrupts cell membranes & inhibits synthesis of protein, inhibit mitosis |
| Hormone therapy | stimulate process of cellular differentiation |
| Alkylating agents | cell cycle-nonspecific |
| Antimetabolites | cell cycle specific |
| Antitumor antibiotics | cell cycle-nonspecific |
| Plant alkaloids | cell cycle specific |
| Nitrosurea | cell cycle-nonspecific |
| Corticosteroids | cell cycle-nonspecific |
| Hormone therapy | cell cycle-nonspecific |
| Miscellaneous | destroys exogenous supply of L-asparagine (cell proliferation) |
| Antiestrogens | suppresses mitosis at interphase |