click below
click below
Normal Size Small Size show me how
Prelim 2 (LEC 12-13)
| Question | Answer |
|---|---|
| Which of the following are extracellular fluids? (Blood plasma, interstitial fluid, intracellular fluid) | Blood plasma, interstitial fluid |
| What is intracellular fluid? | fluid in cells |
| What is interstitial fluid? | fluid between cells |
| What is blood plasma? | fluid in circulation (veins) |
| What makes up extracellular fluids? | water, electrolytes, non-electrolytes (water and solutes) |
| Electrolytes ___ (dissociate/don't dissociate), while non-electrolytes _____ (dissociate/don't dissociate) | dissociate, don't dissociate |
| Which ions generate action potentials? | Na+ and K+ |
| In an action potential ___ is OUTSIDE the cell, while ___ is INSIDE the cell. | Na+, K+ |
| What are extracellular fluids required for? | maintaining cell structure, ensuring cell function, and acting as a vehicle for nutrients and chemicals |
| ____ (hydrostatic/oncotic) pressure maintains tissues and organs in place. | hydrostatic |
| Fluctuation of volume and solutes in ECF is ____ (dangerous/normal). | dangerous |
| Ion loss/gain and water loss/gain are ____ (coupled, independent) | independent |
| (Conformer or Regulator): cells are iso-osmotic with environment, no need for homeostasis | conformer |
| (Conformer or Regulator): exist in unstable environments | regulator |
| What are the 3 parameters regulated by regulators in ECF? | volume of water, ionic concentration, osmotic pressure |
| Fish lose salt by ___ (diffusion/osmosis) and gain water by ____ (diffusion/osmosis). | diffusion, osmosis |
| Fresh water fish ___ (uptake/secrete) Na+ and Cl-, in water, through their gills. | uptake |
| What is the problem of living in fresh water? | salt loss (diffusion) and water gain (osmosis) |
| Fresh water fish ins and outs: | in: salt, water, ions out: water in dilute urine |
| What is the solution to living in fresh water? | diluted urine, uptake of Na+ and Cl- |
| In fresh water fish, Cl- is coupled with ___ and Na+ is coupled with ____. | carbonate, H+ |
| What is the problem of living in sea water? | water loss, salt gain |
| Sea water fish ___ (uptake/secrete) Na+ and Cl-, in water, through their gills. | secrete |
| Fresh water fish ins and outs: | in: water, ions out: salt in scanty urine |
| Low osmolarity environments (fresh water) present a ___ (dilution/concentration) risk? | dilution |
| High osmolarity environments (salt water) present a ___ (dilution/concentration) risk? | concentration |
| What is the solution to living in sea water? | concentrated urine, secretion of Na+ and Cl- |
| What are the two kinds of dehydration? | istonic, hypertonic |
| What is isotonic dehydration? | loss of fluid, no change in concentration (volume drop) |
| Hypovolemia is an example of _____ (isotonic/hypertonic) dehydration. | isotonic |
| What is hypertonic dehydration? | high electrolyte levels |
| What is the other name for hypertonic dehydration? | Hyponatremic (true) dehydration |
| ___ is the method of water/salt intake. | thirst |
| ____ is the mechanism of water/salt output. | extresion |
| Which part of the brain signals dehydration? | hypothalamus |
| What are the steps of dehydration signaling? | hypothalamic thirst center, thirst, water moistens mouth, throat, water absorbed from GI tract |
| What is another name for isotonic dehydration? | hypovolemia |
| Intracellular thirst is ____ (hypertonic or isotonic) dehydration? | hypertonic |
| Extracellular thirst is ____ (hypertonic or isotonic) dehydration? | isotonic |
| What triggers intracellular thirst? | electrolyte concentration too high in ECF |
| What triggers extracellular thirst? | ECF volume too low |
| Hypovolemia uses ____ receptors to trigger feelings of thirst? (extracellular) | baro |
| Hypertonic dehydration uses ____ receptors to trigger feelings of thirst? (intracellular) | osmo |
| Osmoreceptors are HIGHLY sensitive (T or F) | T |
| Osmoreceptors modify their ____ (electrical/chemical) activity, APs, in response to ECF osmolarity. | electrical |
| Cell shrinkage is signal detected by ____ in contact with osmoreceptors | neurons |
| Hypovolemia triggers blood vessel ____ (constriction/dilation). | constriction |
| Hypovolemia triggers heart rate ____ (increase/decrease). | incrfease |
| Hypovolemia is ___ (intra/extra) cellular thirst and induces cravings for ____. | extra, water and salt |
| Hypertonic dehydration is ___ (intra/extra) cellular thirst and induces cravings for ____. | intra, water |
| ___ (carnivores/herbivores) have a deficit of sodium. | Herbivores |
| What are the 3 forms of nitrogenous waste? | ammonia, urea, uric acid |
| What does the urea cycle do? | converts ammonia to less toxic urea |
| The urea cycle is energetically costly. (T or F) | T |
| Ammonia is released through the ____ (whole body surface, kidney, as a paste). | whole body surface |
| Urea is released through the ____ (whole body surface, kidney, as a paste), as ____. | kidney, urine |
| Uric acid is released as a ____ (liquid, solid, paste), which is energetically ____ (costly, favorable). | paste, costly |
| Ammonia is ___ (highly, medium, not very) toxic, requires ___ (high/mid/low) water volume and ___ (high/mid/low) energy. | highly, high, low |
| Urea is ___ (highly, medium, not very) toxic, requires ___ (high/mid/low) water volume and ___ (high/mid/low) energy. | medium, mid, mid |
| Uric Acid is ___ (highly, medium, not very) toxic, requires ___ (high/mid/low) water volume and ___ (high/mid/low) energy. | not very, low, high |
| Urine is made up of 95% ___ and 5% ___ | Water, nitrogenous waste and ions |
| Define excretion | filtration and reabsorption along a tube |
| What are the 4 steps of excretion. | 1. filter ECF, reclaim valuable solutes, reabsorb water, secrete toxin |
| What is the equation for excretion? | Excretion = Filtration - Reabsorption + Secretion |
| What are the 4 steps of excretion. | filtration, reabsorption, secretion, excretion |
| Which tubes connect to the kidney? | renal artery and renal vein |
| What is the input of the kidney? | Blood (renal artery) |
| What are the outputs of the kidney? | Blood (renal vein) and Urine (ureter) |
| The kidney is an assembly of ____. | nephrons |
| What is a nephron? | a basic unit of the kidney |
| Label nephron in order of blood flow. | bowman's capsule, proximal tubule, loop of henle, distal tubule, collecting duct |
| What are the 3 key steps in urine formation? | blood filtration, selective reabsorption and secretion, reabsorption of salt and water |
| Where in the nephron does blood filtration take place? | Bowman's Capsule |
| Where in the nephron does selective reabsorption and secretion take place? | Proximal and Distal tubule |
| Where in the nephron does reabsorption take place? | Loop of Henle and Collecting Duct |
| Where do podocytes exist? | Bowman's Capsule |
| What is a podocyte? | a specialized cell that interacts with endothelial cells |
| What do podocytes do in Bowman's capsule? | form a thin, porous membrane in the inner kidney membrane |
| What is the OUTPUT of Bowman's capsule? | primary urine |
| Colloid oncotic pressure and Capsule pressure ___ (contradict/support) filtration. | contradict |
| ____ (oncotic, hydrostatic) pressure supports filtration (pushes blood out of blood into nephron) | hydrostatic |
| Name the inputs and outputs of the proximal tubule: | in: H+, NH3 out:bicarbonate, water, salt, K+ |
| In the proximal tubule, filtrate volume ___ (increases/decreases), but remains iso-osmotic to blood. | decreases |
| What stays constant in the proximal tubule? | concentration of filtrate |
| What is countercurrent multiplication? | using energy to generate an osmotic gradient to produce a concentrated gradient |
| What is the countercurrent multiplication metaphor? | urine making many U turns in a concentration gradient |
| In a nephron, osmolarity increases _____ (up to down, down to up). | up to down |
| Where does reabsorption of MOST water and solutes occur? | Loop of Henle |
| What are the 3 segments of the Loop of Henle? | 1) descending limb 2) ascending limb 3) thick ascending limb |
| The descending limb of the Loop of Henle is _____ (permeable/impermeable) to water, ____ (permeable/impermeable) to ions. | permeable, impermeable |
| The descending limb of the Loop of Henle is _____ (permeable/impermeable) to water, ____ (permeable/impermeable) to ions. | impermeable, permeable |
| The thick ascending limb of the Loop of Henle actively _____. | pumps out Na+ |
| When the salt concentration increases down the descending loop, water is _____ (gained/lost) | lost |
| In the ascending loop ____ (salt/water) is lost. | salt |
| What is the single effect? | horizontal gradient generated |
| The Loop of Henle goes from a horizontal gradient (___ effect) to a _____ gradient. | single, vertical |
| What are the5 steps of going from single effect to vertical gradient? | 1. isosmotic with blood 2. single effect n1 3. filtration, high salt concentration to bottom 4. single effect n2 5. repeat |
| What happens in step 2 of single effect to vertical gradient? (Single effect n1) | salt gets pumped into the middle, decreases osm in ascending, increases in ascending |
| What enters the distal tubule? | dilute urine |
| What stimulates Na+ reabsorption into the distal tubule? | aldosterone |
| What is aldosterone? | what stimulates Na+ reabsorption in the distal tubule. |
| What are the INPUTS and OUTPUTS of the distal tubule? | in: K+, H+ out: NaCl, bicarbonate, H+, K+ |
| In collecting duct, ____, ____-, and _____ are secreted. | NaCl, Urea, H2O |
| In the collected duct, ___ and ____ leave through passive transport, while ____ leaves through active transport. | Urea, H2O, NaCl |
| When urine enters the Loop of Henle, it is ____ (isoosmotic/hypoosmotic) | isoostomic |
| Hypoosmotic to blood is like saying ____ | dilute |
| When urine exits the Loop of Henle, it is ____ (isoosmotic/hypoosmotic) | hypoosmotic |
| Dehydration triggers the release of ____. | ADH |
| ADH promotes urine ____ (concentration/dilution), retaining water. | concentration |
| How does ADH work? | It triggers aquaporin accumulation at the membrane surface, facilitating water flux and allowing stronger water absorption |
| What kind of channel does ADH trigger? | aquaporin |
| _____ (osmoregulators/osmoconformers) match osmolarity of body to outside environment | Osmoconformers |
| _____ (osmoregulators/osmoconformers) can exist outside of marine environments | Osmoregulators |