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Gynecology
PASS program drill notes
| Question | Answer |
|---|---|
| What does the Seminal Vesicle give to sperm? | Food (fructose) and clothes (semen) |
| What do the Bulbourethral = Cowper's glands secrete? | Bicarbonate (neutralize lactobacilli) |
| What is the purpose of the bicarbonate secreted by the Cowper's glands? | Neutralize lactobacilli |
| What does the Prostate secrete? | "The prostate HAZ it" Hyaluronidase Acid Phosphatase |
| What is the Capacitation reaction? | Zinc is used to peel semen off |
| What is the Acrosomal reaction? | Sperm releases enzymes to eat corona radiata |
| What is the Crystallization reaction? | Wall formed after 1 sperm enters (to prevent polyspermy) the egg |
| Where does Testosterone come from? | Adrenal gland and testicles |
| Where does DHT come from? | Testicles (at puberty) |
| What is a Pseudohermaphrodite? | External genitalia problem; does not match genotype |
| What is a True Hermaphrodite? | Internal genitalia problem ==> has both sexes' genitalia |
| What is a Female Hermaphrodite? | Imposible because the default is female |
| What is the Female Pseudohermaphrodite? | XX with low 21-OHase ==> high testosterone |
| What is a Male Hermaphrodite? | XY with no MIF |
| What is a Male Pseudohermaphrodite? | XY that has low 17-OHase ==> low testosterone |
| What is Hirsutism? | Hairy |
| What is Virilization? | Man-like see in female child |
| What is a testicular Feminization = Androgen insensitivity? | Bad DHT receptor --> XY with blind pouch vagina |
| What is McCune-Albright? | Precocious sexual development, polyostotic fibrous dysplasia "whorls of CT", "Coast of Maine" pigmented skin macules |
| What is Cryptorchidism? | Testes never descended ==> sterility after 15 months, increased risk of seminomas |
| Which stage of the menstrual cycle has the highest estrogen levels? | Follicular stage (has proliferative endothelium) |
| What stage of the menstrual cycle has the highest temperature? | Ovulatory stage |
| What stage of the menstrual cycle has the highest progesterone levels? | Luteal stage (has secretory endothelium) |
| What form of estrogen is highest at menopause? | E1: Estrone (made by fat) |
| What form of estrogen is highest in middle-aged women? | E2: Estradiol (made by ovaries) |
| What form of estrogen is highest in pregnancy? | E3: Estriol (made by placenta) |
| What stage have increased estrogen? | Pregnancy, liver failure, p450 inhibition, obesity |
| What is Adenomyosis? | Growth of endometrium --> myometrium, enlarged "boggy" uterus with cystic areas |
| What does DES take my mom cause in her daughter? | 1. Adenomyosis --> menorrhagia 2. Clear Cell CA of vagina 3. Recurrent abortions from cervical incompetence |
| What is Kallman's syndrome? | No GnRH, anosmia (can't smell) |
| What is Polycystic Ovarian Syndrome? | ↑Cysts: no ovulation --> no progesterone (↑endometrial CA) -> can't inhibit LH, obese, hairy, acne |
| What is Savage's syndrome? | Ovarian resistance to FSH/LH |
| What is Turner's syndrome (XO)? | High FSH, low E2, ovarian dysgenesis |
| What does the Progesterone challenge test tell you? | Bleeds ==> she has estrogen Not bleed ==> shea has no E2 or ovaries 1. ↑FSH --> ovary problem 2. ↓FSH --> pituitary problem |
| What is Sheehan syndrome? | Post-partum hemorrhage --> pituitary, hyperplasia infarcts ---> no lactation |
| What is Asherman's syndrome? | Previous D&C --> Uterine scars |
| What is Oligomenorrhea? | Too few periods |
| What is Polymenorrhea? | Too many periods |
| What is the most common cause of post-coital vaginal bleeding? | Cervical cancer |
| What is the most common cause of post-coital vaginal bleeding in pregnant women? | Placenta previa |
| What is the most common cause of post-coital vaginal bleeding in menopause women? | Endometrial cancer |
| What is Chronic Pelvic Pain? | Endometriosis until proven otherwise |
| What is Dysfunctional Uterine Bleeding? | Diagnosis of exclusion, usually due to anovulation |
| What is Dysmenorrhea? | PG-F cause painful menstrual cramps (teenagers miss school/work) |
| What is Endometriosis? | Painful cyclical heavy menstrual bleeding ==> "powder burns, chocolate cysts" due to ectopic endometrial tissue |
| What is Kleine regnung? | Scan bleeding at ovulation |
| What is menorrhagia? | Heavy menstrual bleeding |
| What are Fibroids = Leiomyoma? | Bening uterus SM tumor 1. Submucosal type => bleeding 2. Subserosa type => pain |