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Chapter 2
Mitosis
| Question | Answer |
|---|---|
| Why do cells divide? | For reproduction, growth, and repair |
| Protects the DNA, a nuclear envelope with a double membrane | Nucleus |
| provides structural support, motility, and regulation | Cytoskeleton |
| helps coordinate cell division, guides chromosomes in mitosis | centrioles |
| What is passed on to daughter cells? | DNA, organelles, cytoplasm, cell membrane, enzymes |
| Nucleus well defined: DNA loosely packed in long chromatin fibers, prepares for mitosis | Interphase |
| cells that grow and mature to divide again | epithelial cells, blood cells, stem cells |
| cells that grow and mature to never divide again | brain/ nerve cells, muscle cells |
| cells that can either divide or never divide again | liver cells |
| "decision making step" in interphase, when the cell decides if it will start the cell cycle or rest or permanently exit the cell cycle | 1st Gap (Growth) |
| DNA replication commences resulting in each chromosome having two sister chromatids | DNA synthesis |
| cells continue to grow and protein synthesis continues in preparation for mitosis | 2nd Gap (Growth) |
| DNA is organized in _____ | chromosomes |
| DNA-protein complex = | chromatin |
| duplicated chromosome: 2 sister chromatids, narrow at centromeres, and contains identical copies of original DNA | Mitotic chromosome |
| dividing cell's DNA between 2 daughter nuclei, "dance of the chromosomes" | mitosis |
| visible chromosomes, nucleolus disappears, nuclear membrane breaks down | prophase |
| in prophase, the ______ move to opposite poles of cell | centrioles |
| in prophase, protein fibers cross cell to form ______ | mitotic spindle |
| coordinates movement of chromosomes and made out of microtubules | mitotic spindle |
| spindle fibers attach to centromeres, microtubules attach to kinetochores, chromosomes begin moving | pro metaphase |
| chromosomes align along middle of cell | metaphase |
| sister chromatids separate at kinetochores, poles move farther apart | anaphase |
| chromosomes arrive at opposite poles: daughter nuclei form, chromosomes disperse, spindle fibers disperse, cytokinesis begins | Telophase |
| constriction belt of actin microfilaments around equator of cell, cleavage furrow forms, splits cell in two | cytokinesis in animals |
| cell plate forms, vesicles fuse to form 2 cell membranes, new cell wall laid down between membranes, new cell wall fuses with existing cell wall | cytokinesis in plants |
| are large protein assemblies that connect chromosomes to microtubules of the mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to its daughters. | Kinetochores |