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Sympathomimetics

Agonist/Antagonist/Mixed

QuestionAnswer
List of Direct sympathomimetics: 1. Albuterol, Salmeterol, Terbutaline 2. Dobutamine 3. Dopamine 4. Epinephrine 5. Fenoldopam 6. Isoproterenol 7. Midodrine 8. Mirabegron 9. Norepinephrine 10. Phenylephrine
Which direct sympathomimetic have a stronger α- affinity? Norepinephrine, Phenylephrine, Midodrine, and
Which direct sympathomimetics have a stronger ß-affinity? -Albuterol, Salmeterol, Terbutaline - Dobutamine - Epinephrine - Mirabegron
Which direct sympathomimetic has ß1=ß2 affinity? Isoproterenol
What is the order of affinity of Norepinephrine? α1>α2>ß1
What is the order of affinity of Dobutamine? ß1>ß2, α
Which direct sympathomimetic is used for Cardiac Stress test in people unable to get on the treadmill? Dobutamine
What is the DOC for anaphylaxis? Epinephrine
Does epinephrine have greater affinity for beta-1 or beta-2 receptors? ß2
What is the half-life of Epinephrine? 2 hours
Which is the problem with Epinephrine? Blood pressure reversal
Epinephrine is often used in treating fatal arrhythmia? VFIB
DOC for Septic shock Norepinephrine
Which has no methyl group, NE, or Epi? Norepinephrine
What is the most common decongestant? Ephedrine
Which indirect sympathomimetic is used to make crystal meth? Pseudo-ephedrine
List of common Indirect sympathomimetics: Amphetamines Cocaine Ephedrine, Pseudo-ephedrine
What is the drug of choice for Neurogenic shock? Phenylephrine
What are the two most common nonselective α blockers? Phenoxybenzamine and Phentolamine
What are the main adverse effects of non-selective α-blockers? Orthostatic hypotension and reflex tachycardia
Which drug treats Pheochromocytoma in preparation for surgery? Phenoxybenzamine
Which drug is often used to diagnose Pheochromocytoma? Phentolamine
What are the main α1-blockers? Prazosin, Terazosin, Doxazosin, and Tamsulosin
What is the only relevant α2-blocker? Mirtazapine
What is the main adverse effect of Prazosin? First dose syncope
What are the DOC for BPH? Terazosin and Doxazosin
Which alpha-1 blocker is used for PTSD? Prazosin
Which α1-blocker has the fewest adverse effects? Tamsulosin
What is the main application of Mirtazapine? Depression in an anorexic patient
Created by: rakomi
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