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Endocrinology
Hypothalamic-Pituitary Hormones - PASS Program
Question | Answer |
---|---|
What is the main function of ADH? | ↑ water permeability of DCT and collecting duct cells in kidney to ↑ water reabsorption |
What is the main function of CRH? | ↑ ACTH, MSH, and ß-endorphin |
What is the main function of Dopamine? | ↓ prolactin and TSH |
What is the main function of GHRH? | ↑ GH |
What is the main function of GnRH? | ↑ FSH, LH |
What is the main function of MSH? | ↑ melanogenesis by melanocytes |
What is the main function of Oxytocin? | 1. Uterine contractions during labor. 2. Milk letdown in response to suckling |
What is the main function of Prolactin? | ↓ GnRH Stimulate lactogenesis |
What is the main function of Somatostatin? | ↓ GH, TSH |
What is the main function of TRH? | ↑ TSH, prolactin |
What is the stimulus for ADH secretion? | ↑ plasma osmolarity |
Which condition does not permit ADH secretion despite ↑ plasma osmolarity? | SIADH |
What is a common cause for a decrease in CRH? | Chronic glucocorticoid steroid use |
What hormone is also called "prolactin-inhibiting factor"? | Dopamine |
What are common adverse effects of Dopamine agonists when used as antipsychotics? | Galactorrhea due to hyperprolactinemia |
What is common use for analog of GHRH? | Treatment of HIV-associated lipodystrophy |
Which pituitary hormone is inhibited by hyperprolactinemia? | GnRH |
Which hormone modulates fear, anxiety, social bonding, mood, and depression? | Oxytocin |
What are the most common symptoms in a woman with a Pituitary prolactinoma? | Amenorrhea, osteoporosis, hypogonadism, and galactorrhea |
What is a strange effect of breastfeeding? | ↑ prolactin --> ↓ GnRH --> delayed postpartum ovulation (natural contraception) |
What hormone analogue is used to treat acromegaly? | Somatostatin |
Which two types of hypothyroidism are seen with elevated TRH? | Primary and secondary hypothyroidism |