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1.6 Mitosis
| Question | Answer |
|---|---|
| Prokaryotic reproduction | binary fission |
| Eukaryotic reproduction | mitosis |
| phases of mitosis where dyad chromosomes are seen | prophase and metaphase |
| phases of mitosis where monad chromosomes are seen | anaphase and telephase |
| dyad chromosome | two identical sister chromatids joined together at centromere |
| monad chromosome | sister chromatid |
| chromatin | linear DNA wrapped around histones |
| phases where chromatin is seen | interphase |
| chromosome | supercoiled DNA |
| phases where chromosomes are seen | mitosis |
| percentage of cell cycle spent in interphase | 90% |
| mitosis | division of the nucleus that results in two genetically identical daughter nuclei |
| subphases of interphase | 1. G1 2. S 3. G2 |
| 4 phases of mitosis | 1. prophase 2. metaphase 3. anaphase 4. telophase |
| Cytokinesis | division of cytoplasm |
| Animal cytokinesis | 1. contractile ring of actin and myosin forms 2. cleavage furrow near old equatorial plane |
| Plant cytokinesis | 1. vesicles containing cellulose meet at old equatorial plate 2. forms temporary cell plate 3. forms cell wall |
| Formula for mitotic index | number of cells in mitosis/ total number of cells |
| Mitotic index indicators | High mitotic index: many cells are dividing (cancer) Lower mitotic index: fewer cells are dividing (controlled) |
| Why do eukaryotic cells use mitosis? | 1. growth 2. asexual reproduction 3. tissue repair 4. embryonic development |
| G0 phase | a resting but fully functional phase where a cell neither divides nor prepares for division |
| G0 phase cell examples | some nerve and smooth muscle cells |
| Tim Hunt | discovered cyclins and how they increased and decreased at different points in the cell cycle |
| Cyclins | family of proteins that control the cell cycle by creating checkpoints |
| Cyclin regulation | cyclins must reach a certain threshold before the cell can begin the next phase of mitosis |
| Cancer | occurs due to uncontrolled mitosis |
| Process of cancer and tumors | carcingens mutate to form cogenes which cause the cell to reproduce uncontrollably |
| Tumor | abnormal mass of cells |
| Primary tumor | original site of cancer |
| Secondary tumor | tumor that started in another part of the body |
| Smoking | positive correlation between smoking and cancer |