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BIO169-Reproduction

Reproduction

QuestionAnswer
What are the 4 different types of sex development? 1) chromosomal sex 2) gonadal sex 3) pheontypic sex 4) psychological sex
What are the factors contritubing to chromosomal sex: at conception, the sperm brings into the ovum either an X chromosome; the ovum contains an X chromosome
What is a chromosomal male? Female? male if the fertilized single-egg ovum (zygote) contains XY chromosomes; if the zygote contains XX chromosomes it is a chromosomal female
what is gonadal sex? it is determined by which type of gonad, ovary or testis, is present
what influences gonadal sex? hormonal factors;
what is an indifferent gonad? early embryos of both sexes have the exact same undifferentiated gonadal tissue
where is the indifferent gonad located? inferior to the developing kidney
which structures will eventually develop into tubular genitalia? Are these specific to sex? no, bot XX and XY embryos have these identical structures: Mullerian ducts, Wolfian ducts, urogenital sinuses, and genital tubercles
what is the SRY gene? it is a gene on the Y chromosome; it is activated approximately 40 days after fertilization
what does the SRY gene do? For which type embryos? the SRY gene is only on the chromosomal male (XY); it directs the gonad to become a testis
how is the testis formed? a substance called Mullerian Regression Factor is produed which causes the Mullerian ducts to break down (i.e. the ducts atrophy)
what does the testis produce to stimulate the development of other male sex organs? after the Mullerian ducts and the testis begins to form, it produces testosterone which causes the development of the Wolffian duct into the inner male structures
what does the Wolffian duct develop into in the male? the epididymis, vas deferens, seminal vesicles, and ejaculatory duct
what does testosterone convert to, and what is its impact on male sex organs? testosterone is converted by enzymes to dihydrotestosterone, which then stimulates the development of the urogenital sinus and genital tubercle (the external male genitalia)
what do the urogenital sinus and genital tubercles become in the male? "urogenital sinus: prostate gland, Cowper's glands, penile urethra and scrotum;
in the XX embryo, what does the undifferentiated gonad become? What triggers this? the undifferentiated gonad becomes an ovary; this occurs because there is no SRY gene activity
what do the Wolffian ducts become in the XX embryo? What triggers this? the Wolffian ducts simply atrophies in the XX embryo; this occurs because of a lack of testosterone
what does the Mullerian duct become in the XX embryo? What triggers this? the Mullerian duct differentiaties into the Fallopian tubes, uterus, and upper vagina; this occurs because of the absence of Mullerian Regression Factor
What do the urogenital sinus and genital tubercle become in the XX embryo? How? "urogenital sinus: lower vagina, labia minora, and labia majora;
is estrogen required in the development of female genitalia? no; it is the absence of the SRY gene, Mullerian regression factor, testosterone, and dihydrotestosterone that cause the development of female genitalia
what is involved with sexuality at a psychological level? 1) sexual identification, 2) sexual preference, 3) libido
explain sexual identification: an individual will develop a self-identity to one sex or the o ther; this is influenced both by genetics and environment
explain sexual preference: the process of developing sexual preference is not completely understood from a physiologica standpoint; it is know that both genetics and environment play a role
explain libido: libido is an individual's sex drive; this is strongly influenced by hormones, most specifically androgens; many psychological factors also play a role
what is phenotypic sex? related to the development of sex organs, excluding ovaries & testis; these remaining sex organs develop into male organs in the presence of Mullerian regression factor, testosterone, and dihydrotestosterone; or into female organs in the lack of these
when does the reproductive system become fully functional? during puberty
why is the reproductive system the last organ system in the body to become fully functional? 1) it is not absolutely essential to supporting life; 2) it is delayed until the individual has completed most other processes related to growth & development and has a body mass & metabolism which can support the demands of reproduction
what prevents the hypothalamus from producing GnRF prior to puberty? the hypersensitivity of the hypothalamus to low levels of sex hormones produced in the immature body; these low levels of sex hormones produce a negative feedback preventing the production of gonadotrophic releasing factors
what stimulates puberty? as puberty approaches, the hypothalamus begins to lose its hypersensitivity and begins to produce increasing amounts of GnRF (FRF and LRF)
what is FRF? LRF? FRF: follicle stimulating hormone releasing factor; LRF: luteinizing hormone releasing factor
What do the increased GnRF levels stimulate? the anterior pituitary to release FSH and LH
What is the role of increasing levels of FSH in the female? FSH stimulates the development of follicles in the ovary; the follicle cells begin to produce estrogen; estrogen stimulates the development of the female secondary sex characteristics
What is the role of FSH on the follicle? it stimulates the maturation of the ovum within each follicle
What is the function of LH? increasing levels of LH will induce ovulation (generally of one ovum); the ruptured follicle cells will produce a temporary endocrine structure called a corpus luteum
What does the corpus luteum produce? large amounts of progesterone
When does the menstrual cycle begin in the female? generally, several years after the onset of development of secondary sex characteristics
what is the role of increasing levels of FSH in the male? it stimulates the seminiferous tubules of the testes to begin spermatogenesis
What is the role of LH in the male? What else is LH called in the male? LH is aka interstitial cell stimulating hormone (ICSH); it stimulates the interstitial cells of the testes to produce testosterone
what is the role of testosterone in the male? it causes development of the male secondary sex characteristics
what are the 3 phases of the menstrual cycle? menstrual phase (days 1-4), proliferative phase (days 5-15), secretory yphase (days 16-28)
what occurs during the menstrual phase? the endometrial lining is shed, FSH levels are rising, follicles develop; as estrogen levels rise, they feedback on the hypothalamus and anterior pituitary and FSH is shut off
what occurs during the proliferative phase? estrogen causes proliferation of the endometrial lining; rising LH levels stimulate ovulation at approximately day 14 and development of the corpus luteum occurs
what occurs during the secretory phase? progesterone from the corpus luteum stimulates the endometrium to become fully functional and able to support a pregnancy; as progesterone levels rise, the feedback on the hypothalamus & anterior pituitary and shut off LH
what triggers the end of the secretory phase, and accordingly, the beginning of the next menstrual cycle? the lack of LH causes the corpus luteum to atrophy and progesterone levels to drop; as progesterone levels drop, it brings about the menstrual phase
Created by: debmurph
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