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CH 28
Assessment of Hematologic Function and Treatment Modalities
| Term | Definition |
|---|---|
| Bone Marrow Aspiration Procedure | Posterior superior iliac crest is the preferred site Client is placed either in lateral position with one leg flexed or in prone position |
| Autosomal Dominant diseases | Factor V Leiden, Familial hypercholesterolemia, hereditary angioedema, hereditary spherocytosis, von Willebrand disease |
| Epoetin Alfa | |
| Megaloblastic Anemia | |
| Monocytes | |
| T Lymphocytes | Responsible for Cell-mediated immunity Recognizes foreign material |
| Basophils | |
| Plasma | Fluid portion of blood 55% Contains albumin, globulin, fibrinogen... necessary for clotting Electrolytes, waste products, and nutrients |
| Decreased Hemoglobin level | Pallor, |
| Neutrophils | WBC capable of phagocytosis; primary defense against bacterial infection |
| Myeloid Stem Cell | Responsible for the production of red blood cells (RBCs) and platelets |
| Cytokines | Proteins from leukocytes, vital to regulate hematopoiesis, apoptosis, and immune responses |
| Erythrocyte | Red blood cell Involved in the transport of oxygen and carbon dioxide to body tissues |
| Erythropoiesis | Process that involves the formation of RBCs Helps Bbone marrow in the production of blood cells |
| Erythropoietin | Hormone produced by the kidney It's necessary for erythropoiesis |
| Fibrin | Forms thrombus and blood clot |
| Fibrinogen | Protein that converts into fibrin |
| Granulocyte | Granulated WBC (neutrophil, eosinophil, basophil) |
| Hematocrit | % of total blood volume of RBCs |
| Hemoglobin | Iron-containing protein of RBCs Delivers O2 to tissues |
| Leukocyte | Aka: WBC Involved in the defense of the body (neutrophils, eosinophils, basophils, monocytes, and lymphocytes) |
| Leukopenia | Less than normal number of WBCs in circulation |
| Lymphocyte | WBC involved in immune functions |
| Oxyhemoglobin | O2 and hemoglobin found in arterial blood |
| Phagocytosis | Process of cellular ingestion and digestion of foreign bodies |
| Plasminogen | Protein that forms plasmin to dissolve thrombi and clots |
| Platelet | AKA thrombocyte Involved in blood coagulation |
| RBC | AKA erythrocyte Involved in the transport of O2 and CO2 |
| Stem cell | Primitive cell, capable of self-replication and differentiation into myeloid or lymphoid stem cell |
| Bone marrow | Site of hematopoiesis 4-5% of total body weight Vascular Involves the pelvis, ribs, vertebrae, and sternum |
| Extramedullary hematopoiesis | Process in which the liver and the spleen resume production of blood when there is a marrow destruction, fibrosis, or scarring |
| Lymphoid stem cells | Produce T/B lymphocytes Have immune functions |
| Myeloid stem cells | Include erythrocytes, leukocytes, platelets Produces blood cells |
| Clinical manifestations for Anemia | Pallor, dizziness, fatigue |
| Stroma | |
| Immature RBCs | |
| Reticular Sites | |
| Vitamin B12 and folic acid Deficiency | Neurological issues, parasthesia |
| Elevation in neutrophils | Bacterial infection |
| Elevation in lymphocytes | Viral infection |
| Bands | Immature WBCs |
| Equimosis | |
| Petechiae | |
| Anaphylaxis |
Created by:
Sharondhg97
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