click below
click below
Normal Size Small Size show me how
Exam 1-3
Genetics
| Term | Definition |
|---|---|
| DNA | Deoxyribonucleic acid, genetic material |
| Proteins | provide an organized structure |
| Chromatin | DNA-protein complex in eukaryotes |
| Eukaryotes | protists, fungi, plants, animals, membrane-bound nucleus, linear chromosomes, mitochondria, lysosomes, Golgi apparatus |
| Prokaryotes | bacteria, archaea, no nucleus, circular chromosomes, nucleoid present, nutrient uptake + waste excretion, rigid cell wall, may have outer membrane or flagellum |
| Mitochondria | ATP synthesis |
| Lysosomes | degradation of macromolecules |
| Golgi apparatus | play role in protein modification + trafficking |
| Cytogenetics | field of genetics that involves microscopic examination of chromosomes, detection of abnormal chromosomes, distinguish btwn 2 species |
| Karyotype | organized representation of chromosomes within a cell from largest to smallest |
| Homologs | members of a pair of chromosomes, nearly identical in size, same banding pattern, same genes, not the same alleles, <1% difference btwn them |
| Locus/Loci | location of a gene on a chromosome |
| Sex chromosomes | X, Y, not homologs, differ in size + genetic composition, short regions of similarity |
| Purpose of cell division? | asexual reproduction + achieving multicellularity |
| Binary fission | cell replicates chromosomes then splits into 2 identical daughter cells |
| G0 phase | either postponed progression or decided to stop dividing |
| S phase | chromosomes are replicated |
| G1 phase | cell prepares to divide, committed to division |
| G2 phase | cell accumulates materials necessary for nuclear + cellular division |
| Chromatids | two copies of replicated chromosomes |
| Phases of Mitosis | prophase, prometaphase, metaphase, anaphase, telophase |
| Interphase | chromosomes decondense + replicate, centrosome divides |
| Mitotic Spindle | microtubules formed by rapid polymerization of tubulin proteins |
| Aster Microtubules | positioning of spindle apparatus |
| Polar Microtubules | help "push" poles away from each other |
| Kinetochore Microtubules | attach to kinetochore, bound to centromere of each individual chromosome |
| Prophase | nuclear envelope dissociates, chromatids condense, centrosomes separate |
| Prometaphase | centrosomes move to opposite ends of cell, forms spindle poles, spindle apparatus forms, kinetochore microtubules grow |
| Metaphase | pairs of sister chromosomes align in the middle of the cell, each pair attached to poles by kinetochore microtubules |
| Anaphase | connection btwn sister chromatids is broken, each chromosome linked to one pole, kinetochores shorten |
| Telophase | chromosomes reach pole of cell + decondense, nuclear membrane separates two new nuclei |
| Cytokinesis | splitting of cell into 2 new cells, animals=cleavage furrow, plants=cell plate |
| Meiosis | sexual reproduction, produce offspring, parents have gametes with 1/2 amount of genetic material |
| Meiotic division | Prophase, prometaphase, metaphase, anaphase, telophase |
| Meiosis 1 | chromosomes separate, forming 4 haploid daughter cells |
| Meiosis 2 | similar to mitosis, but starts with only 1/2 amount of genetic content |
| Synapsis | where homolog pairs line up w/in the cell |
| Homologous Recombination | crossing over |
| Tetrad/Bivalent | pair of sister chromatids |
| Isogamous | produce gametes that are morphologically similar |
| Heterogamous | produce gametes that are morphologically different, sperm/egg |
| Sister chromatids/ Dyads | chromatids joined at a centromere |
| Centrosome | attachment point of the mitotic spindle |
| Mitosis Outcome | 2 genetically identically diploid cells |
| Haploid | 1/2 amount of genetic material |
| Diploid | Has full amount of genetic material |
| Meiosis Outcome | 4 non-genetically identical haploid cells |