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Exam 5
General microbiology - BIO 175
| Question | Answer |
|---|---|
| Function of skin | - Prevents excessive water loss - Regulates temperature - Involved in vitamin D formation - Barrier against microbial invaders |
| Two main layers of skin | 1) Dermis 2) Epidermis |
| Wounds | - Trauma to any tissue of the body (tissue damage) - Allow microbes to infect the deeper tissues of the body |
| Skin microbiota | - Normally harmless microbes present in the skin - Compete with potential pathogens for nutrients and space - Not completely removed through cleansing - Grow in moist areas of the skin - Waste products cause body odor |
| Pyogenic | Produce pus (Staphylococcus aureus) |
| Furuncles | Spread of infections into surrounding tissues |
| Carbuncles | Occur when multiple furuncles grow together |
| Skin microbiota made up of various microbes | - Yeast (malassezia) - Bacteria (staphylococcus, micrococcus, diptheriosis) |
| Skin microbiota can cause disease if | Penetrates epidermis or if immune system is suppressed |
| Caries | Appears as holes or pits in the teeth |
| Periodontal | Gums that are swollen, tender, bright red, or bleeding |
| Tartar | Calcium salts mineralize plaque |
| Respiratory system | Exchanges gases between the atmosphere and the blood |
| Components of the upper respiratory system | 1. Nose 2. Nasal cavity 3. Pharynx 4. Uvula |
| Components of the lower respiratory system | 1. Larynx 2. Trachea 3. Bronchi 4. Alveoli 5. Diaphragm 6. Various protective components (Ciliated mucous membrane, alveolar macrophages and secretory antibodies) |
| Microbiome of LR | Typically organisms are not present |
| Microbiome of UR | - Colonized by many microorganisms - Normal microbiome limits growth of pathogens - Normal microbiome may be opportunistic pathogens |
| Gastrointestinal tract (GI tract) | - The pathways from mouth to the anus - Most organs are protected by de peritoneum |
| Accessory digestive organs | Organs involve in grinding food or providing digestive secretions |
| Gastrointestinal tract | 1. Digest food 2. Absorbs nutrients and water into blood 3. Eliminates waste |
| Components of GI tract | 1. Mouth 2. Esophagus 3. Stomach 4. Small intestine 5. Large intestine 6. Rectum and anus |
| Accessory of digestive organs | 1. Tongue and teeth 2. Salivary glands 3. Liver 4. Gallbladder 5. Pancreas |
| Esophagus, stomach and duodenum | - These regions are more free of microbes - Peristalsis and rapid transport of food help prevent microbial colonization |
| Tongue, teeth, jejunum, ileum, colon and rectum | Viridans streptococci are most prevalent in this region |
| Lower intestines and colon | - Microbiota here are microbial antagonist -Mucous membrane prevents entry of microbes into the bloodstream |
| Axenic | Low respiratory organs |
| What causes life-threating illness? | Bacterial of the lower respiratory system |
| Three types of tuberculosis | 1) Primary 2) Secondary 3) Disseminated |
| Primary Tuberculosis | Formation of small, hard nodules (tubercles) in lungs |
| Secondary Tuberculosis | Bacterium rupture from tubercles and reestablish active infection in lungs |
| Disseminated | - Macrophages carry bacterium to bone marrow , kidneys, spleen, spinal cord, and brain - Results in wasting away of body (consumption) |
| Bacterial gastroenteritis | Inflammation of stomach or intestines (associated with contaminated food) |
| Antimicrobial-Associated Diarrhea toxins | Toxins mediate inflammation and pseudomembrane formation |
| Toxin A | Breaks down junctions between epithelial cells resulting in inflammation and fluid loss (diarrhea) |
| Toxin B | Kills epithelial cells and induces formation of lesions (pseudomembrane colitis) |
| Norovirus | - Non enveloped -Positive-sense, single-stranded RNA virus |
| Rotavirus | - Nonenveloped - Double-stranded, segmented RNA virus |