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Gastrulation Pattern

Bio 3 Lecture 4

QuestionAnswer
What are the different stages involved in vertebrate development? Fertilization, cleavage, gastrulation, neurulation, organogenesis
What is fertilization and what are the 3 events that happen? The fusion of a male and female gametes. 3 events: (1) Sperm penetration and membrane fusion (2) Egg activation (3) Fusion of nuclei
[Fertilization stages] What happens during sperm penetration and membrane fusion? (see image to identidy the parts) The passage of sperm through 2 protective egg layers: The corona radiata zone and the zona pellucida
[Fertilization stages] What does the acrosome of the sperm contain? Digestive enzymes
[Fertilization- Sperm penetration] Where does the sperm nucleus enters? The egg's cytoplasm
[Fertilization- Egg activation] What blocks the polyspermy? The release of Ca 2+ which alters the egg's coat
[Fertilization- Egg activation] The chromosomes are stimulated to continue what? the second meiotic division
[Fertilization- Egg activation] What happens during egg activation, part one of Release of Ca+ ? Increase in protein synthesis and metabolic activity. Rotation of cytoplasm
[Fertilization- Fusion of nuclei] Where do the sperm and egg nuclei migrate to? What happens when they fuse? They migrate towards each other and form the diploid zygote when they fuse.
[Cleavage] What does the embryo have (poles)? Animal pole (external tissues) and vegetal pole (internal tissue)
How does the blastula happen? When does it happen? The blastomeres pump Na+ into the intracellular spaces which draws water. This results in a hollow ball of cells, aka a blastula (with the blastocoel). Happens during cleavage.
What are cleavage pattern influenced by? The amount of yolk in the egg
What do eggs with high amounts of yolk undergo? Meroblastic (incomplete) cleavage
What is it called when the cytoplasm concentrates at one pole? What does it result in? The blastodisc. It results in the embryo not being spherical
What do eggs with moderate to little amounts of yolk undergo? What's the shape of the embryo? Example. Holoblastic (complete) cleavage. The embryo is spherical and mammals have holoblastic cleavage
What is gastrulation? It's a serie of cell shape changes and cell movements in the blastula
Cells move during gastrulation using a variety of cell shape changes, what are they? (see slide 15) (1) Invagination (2) Involution (3) Delamination
What do gastrulation patterns depend on? The amount of yolk
What do gastrulation in sea urchins form? They have yolk-poor eggs, so they form hollow symmetrical blastulas
From what does the embryo develop in mammals? From the inner mass of cells
What happens when inner mass of cells flattens? It delaminates into 2 layers and the primitive streak forms
The cell movement gives rise to what? See slide 17 to visualize! The 3 primary germ layers (Ectoderm, mesoderm and endoderm)
What is organogenesis? The formation of organs (which happens just after gastrulation)
How does organogenesis happen? Occurs by interaction of cells within and between the three germ layers
What determines the cell's fate? How can a cell fate be established? The location of the cell in the developping embryo. A cell's fate can be established by interactions with neighboring cells
Where does organogenesis begin and what structures develop? Organogenesis in vertebrates begins with neurulation where the notochord, the neural tube develop and the neural crest.
What is the notochord, neural crest and the neural tube? The notochord provides structural support and site of attachment of skeletal muscles. The neural tube will form the spinal cord. The neural crest forms the PNS (peripheral nerve system).
Identify the notochord, neural tube and neural crest see slide 19
How long does human development takes form fertilization to birth? How many trimesters? 266 days, aka 9 months. 3 trimesters
[Extraembryonic membranes] What is the amnion? It encloses the amniotic fluid
[Extraembryonic membranes] What is the chorion? It contributes to the placenta in mammals
[Extraembryonic membranes] What is the yolk sac? It's the food source in bird embryo (also found in mammals but not nutritive)
[Extraembryonic membranes] What is the allantois? In birds, it forms a structure for gas exchange (replaces the placenta). In mammals, it contributes to blood vessels in the umbilical cord
[Extraembryonic membranes] Identidy the location of the amnion, the chorion, the yolk sac and the allantois See slide 23
[Month 1, Week 1-Trimester 1] What happens to the zygote? After 6-7 days? Where does the blastula travel to? It undergoes its first cleavage about 30 hrs after fertilization. After 6-7 days, it has differentiated into a blastocyst. The blastula travels to the endometrium in the process known as implantation
What is implantation? A process where the blastula travels to the endometrium
[Month 1, Week 2-Trimester 1] What develops during that time? What stage of development occurs? The developing chorion and the mother's endometrium engage to form the placenta. Gastrulation occurs in week 2.
[Month 1, Week 2-Trimester 1] What happens to the moms and the babys blood? They come into proximity but do not mix; gases are exchanged.
What week do neurulation and organogenesis happen? Neurulation in week 3 and organogenesis in week 4
[Month 2-Trimester 1] What is established? What is the size/weight of embryo? What does the embry become? Organogenesis continues: miniatuare limbs and major organs in the body are established. Embryo is 25 mm and 1g. At week 9, the embryo becomes a fetus.
[Month 3-Trimester 1] What system develops and what moves? The nervous system develops and limbs start to move
[Trimester 2] What develops? The basic body develops and the bones enlarge in the 4th month. Rapid fetal heartbeat
[Trimester 3] What is this period? What happens to the weight of fetus? What is formed? It's a period of growth and organ maturation. The weight doubles several times. The major verbe tracts in the brain are formed.
[Trimester 3] What continues to develop months after the birth? The brain continues to develop and produce neurons
During the birth, what does the mother's uterus releases? What does it do? Releases prostaglandins. They begin uterine contractions.
What does the sensory feedback from uterus stimulates? It stimulates oxytocin release from posterior pituitary
What further stimulates uterine contractions? Oxytocin and prostaglandins
What expels the fetus? Strong contractions (aided by the mother's voluntary pushing)
What continues after birth? Uterine contractions continue to expel the placenta and associated membranes
What are the birth stages? (1) The cervix relaxes causing it to dilate and thin out (2) Uterine contractions increase in strength and the enfant is delivered (3) The placenta is expelled
Created by: Malayka
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