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Genetics Bio 300

Chromosomes and Cellular Reproduction

QuestionAnswer
genome contains complete set of genetic information for any organism. encoded in Nucleic acids
transmission genetics classic genetics, basic principles of heredity and how traits are passed from one generation to the next. Addresses relationship between chromosomes and heredity, arrangement of genes on chroms. and gene mapping.
molecular genetics chemical nature of gene itself. how genetic info is encoded, replicated and expressed. included cellular process of transcription and translation.
population genetics explores genetic composition of groups of individual members of same species and how they change over time
model genetic organisms organisms having characteristics that make them particularly useful for genetic analysis and with a tremendous amount of genetic info has accumulated. ex. drosophila and e.coli
pangenesis theory of particules, gemmules, carry info from various parts parts of the body to reproductive organs which are then passed to embryo.
inheritance of acquired characteristics pangenesis led to this theory in which traits acquired in one's lifetime were passed on to offspring
preformationism inside the egg or sperm there exists a tiny adult which enlarges.
Hopi culture contributed to high incidence of albinism by giving albinos special status and praise. It was considered positive so breeding was encoraged.
When and where did agriculture first rise? What role did genetics play in development of first domesticated animals and plants? In the middle east approx. 10,000 and 12,000 years ago. produced several hundered varieties of palms.
Germ plasm theory cells in the reproductive organs carry a complete set of genetic info that is passed to the egg and sperm
blending inheritance offspring are a blend, or mixture, of parental traits
relationship between genetics and evolution Evolution is due to genetics and heredity. Through genetic variation and mutations evolution arises
Prokaryotic no nucleus, small cell diameter, No complex histones, small amount of DNA, membrane-bound organelles and cytoskeleton are absent
Eukaryotic nucleus, large cell size, multiple linear DNA with complex histones, Membrane bound organelles and cytoskeleton are present
Viruses simple structures composed of outer protein coat surrounding nucleic acid. reproduce only in hosts. The close relationship of viruses to their hosts make them useful for studying the genetics of host organisms
Fundamental Events in Cell Reproduction 1. genetic info copied 2. copies must be separated from each other 3. cell must divide
Prokaryote Cell Reproduction Begins at Origin of Replication 2 newly replicated chroms move away from each other towards opposite ends of cell. A new cell wall forms between them producing 2 new cells
Homologous Pair Each chrom in one set has a corresponding chrom. Usually alike in structure and size and each carry genetic info for the same set of hereditary characteristics
Diploid and Haploid Diploid contains two sets of genetic info. Haploid contains one set of genetic info
Functional Chromosomes elements Centromere (point of attachment for spindle) Pair of Telomeres Z(natural ends or tips of linear chromosomes stabilize chrom ends) Origins of Replication (sites where DNA synthesis begins not easily observed)
Sister chromatids 2 identical copies of chromosome - X
Interphase extended period of growth and development b/w cell divisions. 3 stages G1( cell grows proteins synthesized), S (chromosomes duplicate) G2 (prepare for mitosis biochemical events)
M Phase 5 stages of Mitosis and cytokinesis
1. Prophase chromosomes condenses possessing 2 chromatids. Mitotic spindle forms out of a pair of centrosomes that migrate to sides of cell. With in each centrosome is a special organelle centriole composed of microtubules
2. Prometaphase nuclear membrane disintegrates, spindles enter nuclear region and microtubules make contact with chroms. microtubules lengthen and shorten moving chroms about.
3. Metaphase chroms become arranged in a single plane "the metaphase plate"
4. Anaphase sister chromatids separate and move to opposite sides
5. Telophase arrival of chroms at separate poles. nuclear envelope reforms. chroms relax.
Cytokinesis cell division of cytoplasm
Genetically important results of cell cycle 1 cell produces 2 cells containing same genetic info because S phase creates exact copy of existing DNA
Sexual Reproduction 2 divisions - 2 processes: meiosis which leads to gametes and chromosome number reduces by half. then fertilization in which gametes fuse and restore chroms to original diploid value
Prophase I contains 5 substages, leptotene(chromosome contract and become visible) Zygotene(chroms continue to condense) Pachytene(chroms become shorter and thicker) CROSSING OVER TAKES PLACE. Diplotene(centromeres of paired chromes move apart. diakinesis (condense
crossing over results from centromeres moving apart in diplotene and homologs stay attached only at chiasma
Metaphase I align at metaphase plate
Anaphase I separation of HOMOLOGOUS chroms and move to opposite poles
Telephase I Arrive at spindle poles and cytoplasm divides
heredity influences our lives in sign ways - hair color, eye color, how the environment affects us
model genetic organism characteristics haploid, short gen time, manageable in number, easy to handle in lab, inexpensive
3 domains of life eubacteria, archaea, eukarya
allele multiple forms of a gene
gene fundamental unit of heredity. found on chromosomes but can also be found on extra-chromosomal elements
nucleic acids carry out genetic info
polygenic characteristics characteristics encoded by genes at many loci
Continuous or quantitative characteristics characteristics having many possible phenotypes and exhibit a continuous distribution of phenotypes like height.
multifactorial traits polygenic characteristics (encoded by genes on many loci) that are influenced by the environment because each genotype has a broad norm of reaction.
exceptions in bacteria linear and multiple chromosomes can be found as well as membrane bound organelles
histones 2 parts. DNA wraps around it condensing then it is locked in. The entire unit of Histone and DNA is called chromatin.
telocentric Chromosome shaped like a U
Metacentric chromosome shaped like an X
Created by: loveflyny
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