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Second set

Medications

QuestionAnswer
Etomidate class hypnotic, anesthesia induction
Etomidate or Amidate
Etomidate action Effects seem to be similar to GABA
Etomidate indications Rapid Sequence Intubation sedation,pharacological assisted intubation, Induction of anesthesia
Etomidate Adverse Effects May cause hypotension, respiratory depression, pain at the site of injection, temporary involuntary muscle movements, and frequent nausea/vomiting on emergence, adrenal insufficiency, hyperventilation, apnea of short duration, laryngospasm, snoring.
Etomidate Contraindications Known sensitivity, use in pregnancy if the potential benefits justify the potential risks of the fetus, and labor/delivery.
Etomidate Dosage: Adult: 0.2-0.6mg/kg IV, IO (over 30-60 seconds) a typical intubation dose is 20mg slow IV, consider less (e.g. 10mg) in elderly or patients with cardiac conditions.
Etomidate Dosage: Pedi: >10 years, same as adult, <10 years, safety has not been established.
Etomidate Special Considerations Personnel and equipment must be present to manage the patient's airway before administration, pregnancy class C.
Midazolam Versed
Midazolam Class Benzodiazepine schedule C-IV
Midazolam Action Binds to benzodiazepine and enhances the effects of the brain chemical, GABA. Benzodiazepines act at the level of the limbic, thalamic, and hypothalamic regions of the CNS-provides short CNS depression (including sedation, skeletal muscle rela
Midazolam Indications Sedation, anxiety, skeletal muscle relaxation.
Midazolam Adverse Effects Respiratory depression, respiratory arrest, hypotension, nausea/vomiting, headache, hiccups, cardiac arrest.
Midazolam Contraindications Acute narrow angle glaucoma, pregnancy, known sensitivity.
Midazolam Dosage Sedation: Adult: Healthy and < 60 years 1mg IV, IO. No more than 2mg should be given over a 2 minute interval. (Max dose 5mg).
Midazolam Dosage Sedation: Adult: >60 years, or debilitated or chronically ill: 1mg IV, IO and no more than 1.5mg given over a 2 minute period. Additional should be given at a rate of no more than 1mg oer a 2 minute period. (Max dose 3.5mg).
Midazolam Dosage Pedi: 12-16 years Same as adult.
Midazolam Dosage Pedi: 6-12 years: 0.025-0.05mg/kg IV, IO up to a total of .4mg/kg. Exceeding 10mg total dose usually not necessary.
Midazolam Dosage Pedi: 6mos-5 years: 0.05-0.1mg/kg IV, IO up to a total dose of 0.5mg/kg. Exceeding 6mg as a total dose usually not necessary.
Midazolam Dosage Pedi: <6 mos Because this age group is especially vulnerable to airway obstruction and hypoentilation, use small incriments with frequent clinical evaluation. Dose: 0.05-0.1mg/kg IV, IO.
Midazolam Special Considerations Frequent monitoring of vital signs and pulsoximetry. Be prepared to support the patient's airway and ventilation. Pregnancy class D.
Succinylcholine also known as Anectine
Succinylcholine Class Neuromuscular blocker, depolarizing
Succinylcholine Action It competes with acetylcholine receptor of the motor end plate on the muscle cell, resulting in muscle paralysis.
Succinylcholine Adverse Effects Anaphylactic reactions, respiratory depression, apnea, bronchospasm, cardiac arrhythmias, malignant hyperthermia, hypertension, muscle fasciculation, post procedure m uscle pain, hypersalivation, rash.
Succinylcholine Contraindications Malignant hyperthermia, burns, trauma. Caution in children, cardiac, hepatic, renal, and peptic ulcer disease, cholinesterase-inhibitor tox., pseudocholinesterase dfncy, digitalis tox., glaucoma, hyperkalemia, hypothermia, rhabdomyolysis, myathenia gravis
Succinylcholine Dosage: Adult: IV: 0.6mg/kg IV, IO (range 0.3-1.1mg/kg).
Succinylcholine Dosage: Adult: IM: 3-4mg/kg (max dose 150mg).
Succinylcholine Dosage: Pedi: IV: Adolescent and older children: 1mg/kg IV, IO
Succinylcholine Dosage: Pedi: IV: Small children and infants: 2mg/kg IV, IO
Succinylcholine Dosage: IM: 3-4mg/kg (max dose 150mg).
Succinylcholine Special Considerations: IV administeration: Results in neuromuscular blockade in 0.5-1 minute.
Succinylcholine Special Considerations:IM administeration: Results in neuromuscular blockade in 2-3 minutes.
Succinylcholine Special Considerations: IV administeration in infants and children: Can potentially result in profound bradycardia, and in shome cases, asytole. The incidents of bradycardia are greater after the 2nd dose. Occurrence of bradycardia can be reduced w ith pretreatment of Atropine.
Succinylcholine Special Considerations Can have a s ignificant prolonged effect in the setting of poisoning with nerve gas agents organophosphate pesticides. Pregnancy class C.
Vecuronium also known as Norcuron
Vecuronium Class Neuromuscular blocker, non-depolarizing
Vecuronium Action It antagonizes acetylch9oline at the motor end plate, producing skeletal muscle paralysis.
Vecuronium Indications To induce meuromuscular blockade for facilitation of ET intubation.
Vecuronium Adverse Effects Muscle paralysis, apnea, dyspnea, res piratory depression, sinus tachycardia, urticaria.
Vecuronium Contraindications Known sensitivity to bromides. Caution with heart disease and liver disease.
Vecuronium Dosage: Adult: 0.08-0.1mg/kg IV< IO.
Vecuronium Dosage: Pedi: Dosage is individualized.
Vecuronium Special Considerations Pregnancy class C
How do you spell the other name of Vecuronium? Norcuron
How do you spell the other n ame of Norcuron? Vecuronium
Calcium Chloride/Gluconate Class Electrolyte solution
Calcium Chloride/Gluconante Action Counteracts the toxicity of a hyperkalemia patient by stabilizing the me mbranes of the cardiac cells, reducing the likelihood of fibrillation.
Calcium ChlorideGluconate Indications Hyperkalemia, hypocalcemia, hypomagnesemia.
Calcium Chloride/Gluconate Adverse Effects Soft tissue necrosis, hypotension, bradycardia (if administered too rapidly).
Calcium Chloride/Gluconate Contraindications VI, Digitalis toxicity, hypercalcemia.
Calcium Chloride/Gluconaate Recommended Dose: Supplied as a 10% solution; therefore, each ml contains 100mg of Calcium Gluconate
Calcium Chloride/Gluconate Dosage: Adult: 500-1000mg IV, IO administered slowly at a rate of a pprox 1-1.5ml/minute. (Max dose 3g IV, IO).
Calcium Chloride/Gluconate Dosage: Pedi: 60-100mg/kg IV, IO slowly over a 5-10 minute period. (Max dose 3g IV, IO).
Calcium Chloride/Gluconate Special Considerations Do not administer by IM or subQ routes w hich causes significant tissue necrosis. Pregnancy class C.
Pancuronium, also known as Pavulon
How do you spell the other name for Pancuronium? Pavulon
How do you spell the other name f or Pavulon? Pancuronium
Pancuronium Class Non-depolarizing neuromuscular blocker
Pancuronium Action Antagonized acetycholine at the motor end plate, producing skeletal muscle paralysis.
Pancuronium Indications To induce neuromuscular blockage for the facilitation of ET intubation.
Pancuronium Adverse Effects Muscle paralysis, a pnea, dyspnea, respiratory depression, cutaneous flushing, sinus tachycardia.
Pancuronium Dosage: Adult: 0.04-0.1mg/kg IV, IO; repeat dosing is 0.01 mg/kg every 25-60 minutes.
Pancuronium Dosage: Pedi: Same as adult dosing.
Pancuronium Special Considerations Pregnancy class C.
Magnesium Sulfate, also known as MgS04
How do you spell the other name for MgS04? Magnesium Sulfate
Magnesium Sulfate Class Electrolyte, tocolytic, mineral
Magnesium Sulfate Action Required for normal physio function. MgS04 is a cofactor in n eurochemical transmission and muscular excitability. Controls s eizures by blocking peripheral neuromuscular transmission. Also a peripheral vasodialator and inhibitor of platelet function.
Magnesium Sulfate Indications Torsades de Pointes, cardiac arrhythmias associated with hypomagnesemia, eclampsia, and seizure prophylaxis in preeclampsia, status asthmaticus.
Magnesium Sulfate Adverse Effects Magnesium toxicity (signs include flushing, diaphoresis, hypotension, muscle paralysis, weakness, h ypothermia,and cardiac,, CNS or respiratory depression).
Magnesium Sulfate Contraindications AV block, GI obstruction. Use with caution in renal impairment.
MgS04 Dosage: Ventricular fibrillation/pulsel4ess ventricular tachycardia with Torsades de Pointes or hypomagnesemia: Adult: 1-2g in 10ml D5W IV, IO administered over 5-10 minutes.
Magnesium Sulfate Dosage: Ventricular fibrillation/pulseless ventricular tachycardia with Torsades de Paontes or hypomagnesemia: Pedi: 25-50mg/kg IV, IO over 10-20 minutes. May administer faster for Torsades de Pointes (max single dose 2g).
Magnesium Sulfate Dosage: Torsades de Pointes witha pulse or chardiac arrhythmias w ith h ypomagnesemia: Adult: 1-2g in 50-100ml D5W IV, IO administered over 5-60 minutes. Follow with 0.5-1g/hr IV, IO titrated to control Torsades de Pointes.
Magnesium Sulfate Dosage: Torsades de Pointes w ith a pulse or cardiac arrhythmias with hypomagnesemia: Pedi: 25-50mg/kg IV, IO over 10-20 minutes (max single dose 2g).
Magnesium Sulfate Dosage: Eclampsia and seizure prophylaxis in preeclampsia: Adult: 4-6g IV, IO over 20-3- minutes, followeeed by infusion of 1-2g/hr.
Magnesium Sulfate Dosage: Status asthmaticus: Adult: 1.2-2g slow IV, IO (over 20 minutes).
Magnesium Sulfate Dosage: Status asthmatius: Pedi: 25-50mg/kg (diluted in D5W) slow IV, IO (over 10-20 minutes).
Magnesium Sulfate Special Considerations Pregnancy class A
Terbutaline Sulfate, also known as Brethine
How do you spell the other name for Terbutaline Sulfate? Brethine
How do you spell the ot her name for Brethine? Terbutaline Sulfate
Terbutaline Sulfate Class Adrenergenic agonist
Terbutaline Sulfate Action Stimulates the beta 2 receptor, producing relaxation of bronchial smooth muscle and bronchodialation.
Terbutaline Sulfate Indications Prevention and reversal of bronchospasm.
Terbutaline Sulfate Adverse Effects Cardiac arrhythmias, arrhythmia exacerbation, angina, anxiety, headache, tremor, palpitations, dizziness.
Terbutaline Sulfate Contraindications KNown sensitivity to sympathomimetics. Use caution in hypertension, cardiac disease, cardiac arrhythmias, diabetes, elderly, MAOI therapy, phenochromocytoma, thyrotoxicosis, seizure disorders.
Terbutaline Sulfate Dosage: Adult: 0.25mg subQ every 20 minutes for 3 doses. The usual site for subQ injections is the lateral deltoid.
Terbutaline Sulfate Dosage: Pedi: 0.01mg/kg subQ every 20 minutes for 3 doses.
Terbutaline Sulfate Special Considerations Pregnancy class B
Created by: 1300311346