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83 — Ch. 15
CNS Drugs
| Question | Answer |
|---|---|
| 5 benzodiazepines for anxiety? | Clonazepam, Lorazepam, Diazepam, Chlordiazepoxide, Alprazolam |
| 3 benzodiazepines for anxiety? | Zolpidem, Zaleplon, Eszopiclone |
| Melatonin agonist for insomnia? | Ramelteon |
| Define Parkinson's Disease. | neurodegenerative disorder of the extrapyramidal system associated w/ disruption of neurotransmission in the striatum |
| 2 major categories of PD drug therapy? | dopaminergic agents, anticholinergic agents |
| Example of dopaminergic PD drug? | Levodopa |
| Example of anticholinergic PD drug? | Trhexyphenidyl |
| How do anticholinergic PD drugs work? | prevent activation of cholinergic receptors |
| Most important therapeutic consideration for epilepsy? | seizure frequency chart |
| What 7 drugs should NOT be mixed with grapefruit juice? | -dipines, Verapamil, Carbamazepine, Buspirone, Lovastatin |
| 3 local anesthetics? | Lidocaine, Procaine, Cocaine |
| 4 general anesthetics? | Halothane, Nitrous Oxide, Propofol, Ketamine |
| 2 inhaled general anesthetics? | Halothane, Nitrous Oxide |
| 2 IV general anesthetics? | Propofol, Ketamine |
| 5 steps, in order, of loss of perception during local anesthesia? | 1. pain 2. cold 3. warmth 4. touch 5. deep pressure |
| 2 principal AE of general anethetics? | respiratory compromise, decreased cardiac performance |
| What is Myasthenia Gravis characterized by? | fluctuating muscle weakness & predisposition to rapid fatigue |
| What is Myasthenia Gravis? | autoimmune disorder that attack nicotinic-M receptors on skeletal muscle |
| 2 similar symptoms of muscarinic & cholinergic crises? | muscle weakness, paralysis |
| How to differentiate between muscarinic & cholinergic crises? | hx of muscarinic meds, challenging dose of edrophonium, medic alert bracelet |
| 3 main classes of opioid receptors? | Mu, Kappa, Delta |
| Strong opioid agonist? | morphine |
| Moderate to strong opioid agonist? | codeine |
| 7 adjuvant analgesics? | NSAIDs, antihistamines, tricyclic antidepressants, anti-seizure drugs, local anesthetics, muscle relaxants, corticosteroids |