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Mendelian Genetics
Biology in Focus Ch. 11
| Term | Definition |
|---|---|
| True breeding | organisms that always produce offspring having the exact same traits |
| P generation | the parental generation in genetics experiments |
| F1 generation | the first generation of offspring in genetics experiments |
| F2 generation | the second generation of offspring and genetics experiments, these are the children of the F1 generation |
| Alleles | alternate versions of a gene |
| Dominant allele | determines an organism's appearance |
| Recessive allele | has no noticeable effect on an organism's appearance because it is masked by the dominant trait |
| Law of Segregation | one of Mendel's laws that states the two alleles for a heritable character separate from each other during gamete formation and end up in different gametes |
| Punnett square | a chart used to predict allele composition of offspring during a genetics cross |
| Homozygous | has two of the same alleles for a trait |
| Heterozygous | has two different alleles, one dominant one recessive for a trait |
| Phenotype | an organism's outward appearance or observable traits |
| Genotype | and organism’s genetic makeup |
| Locus | the location of a gene on a chromosome |
| Test cross | a technique used to determine the genotype of an unknown organism by crossing it with a homozygous recessive, and analyzing the resulting offspring |
| Monohybrid | being heterozygous for one particular trait |
| Monohybrid cross | a mating between two heterozygotes |
| Dihybrid | individual who is heterozygous for two traits |
| Dihybrid cross | a mating between two organism who are heterozygous for two traits |
| Law of Independent Assortment | Mendel's law that states that two or more genes separate (segregate) independently of any other genes during gamete formation |
| Multiplication Rule | to determine the probability of multiple events, multiply each of their probabilities together. |
| Complete dominance | phenotypes of homozygous dominant and heterozygous individuals are the same |
| Incomplete dominance | heterozygotes have a phenotype in between those of the two parents |
| Codominance | inheritance pattern where heterozygous individuals show both traits at the same time. |
| Hybrid | synonym for heterozygous individual |
| Multiple alleles | when more than one allele affects gene expression |
| Pleiotropy | a single gene can have multiple different effects on phenotype expression (a single gene can do more than one job) |
| Epistasis | a gene at one locus can alter the phenotypic expression of a gene at a completely different locus. |
| Polygenic inheritance | two or more genes influence a single phenotypic character; phenotypic expression has spectrum. |
| Pedigree | a genetic family tree that uses squares for males, circles for females, and color codes affected individuals. |
| Carrier | an organism who does not show signs of a disease, but does have a chance to pass a recessive gene onto its offspring because they are heterozygous. |
| Cystic Fibrosis | the most common lethal genetic disease in the US; results in thick mucus coating in the organs. |
| Sickle Cell Disease | most common genetic disorder among individuals of African descent. The shapes of the red blood cells are affected impacting oxygen transport |
| Huntington's Disease | a dominantly inherited lethal condition that results in the degeneration of nervous system tissue |