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Cell Systems
| Question | Answer |
|---|---|
| how are proteins secreted from the cell? | proteins meant to be secreted move through the secretory pathway: 1. protein enters ER 2. protein exits ER 3. Protein enters golgi apparatus 4. protein exits golgi apparatus 5. protein is secreted from cell. |
| how are proteins targeted to the ER? | Proteins are targeted through the ER signal sequence(Zip code) short sequence produced at N-terminus |
| how are proteins sorted in the Golgi apparatus? | 1. proteins bound for different destinations carry distinct tags 2. proteins are sorted 3. transport vesicles bud 4. cytosolic and membrane proteins cause transport vesicles to attach and fuse at destinations. 5. vesicles deliver contents |
| how are proteins imported into the nucleus? | |
| Actin filaments(microfilaments) | move cells via muscle contraction or cell crawling |
| Intermediate filaments | resist tension |
| Microtubules | move cells via flagella or cilia move chromosomes during cell division provide tracks for intracellular transport |
| what motor protein is associated with actin filaments(microfilaments)? | Myosin(cellular movement): which converts chemical energy to kinetic energy uses ATP to make movements happen |
| what motor protein is associated with microtubules? | Kinesin(intracellular transport): walks along a microtubule track requires ATP |
| Nuclear pore complex(NPC) | regulates import/export |
| what do the proteins to be imported into the nucleus contain? | a nuclear localization sequence(NLS) |
| The Endomembrane system | protein sorting, packaging, shipping, and recycling |
| steps of the endomembrane system | Rough ER---> Golgi apparatus---> Vesicles--->Destination(organelles or plasma membrane) |
| where are proteins made? | Proteins are made in the rough ER |
| where are proteins sorted? | Proteins are sorted in the Golgi apparatus |
| where are proteins transported to? | Proteins are transported to the vesicles. |
| Glycosylation | proteins become glycoprotein. |
| where are microtubules made? | In the microtubule-organizing center(MTOC) plants have many while animals only have centrosome(two centrioles) |