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Pharmacology Ch2
Based on Lilley's Pharmacology for Canadian Health Care Practice 4th ed
Term | Definition |
---|---|
Agonist | Drugs that bind to and stimulate the activity of one or more receptors in the body |
Adverse drug reaction | Any unexpected, undesired, unintended, or excessive response to a medication given at therapeutic dosages |
Antagonists | Drugs that bind to and inhibit the activity of one or more receptors in the body; also called inhibitors |
Antagonistic effects | Drug interaction in which the effect of a combination of two or more drugs is LESS than the sum of the individual effects of the same drugs given alone; usually caused by one drug blocking the effect of the other |
Chemical name | The name that describes the chemical composition and molecular structure of a drug |
Contraindication | Any condition, especially one that is a result of disease state, patient characteristics, including recent or current drug therapy that renders a form of treatment improper or undesirable |
Drug | Any chemical that affects the physiological processes of a living organism |
Drug classification | A method of grouping drugs based on structure or therapeutic use |
Drug interaction | Alteration of pharmacological or pharmacokinetic activity of a given drug caused by presence of one or more additional drugs |
Generic name | The name given to a drug approved by Health Canada; aka non-proprietary name or the official name |
Half-life | The amount of time it takes for the blood level of a drug to be reduced by 50% |
Idiosyncratic reaction | An abnormal and unexpected response to a medication, other than allergic reaction, that is peculiar to an individual patient |
Medication error | Any preventable adverse drug event involving inappropriate medication use by a patient or health care provider; may or may not cause patient harm |
Onset of action | The time required for a drug to elicit a therapeutic response after dosing |
Peak effect | The time required for a drug to reach its maximum therapeutic response in the body |
Pharmaceutics | The science of preparing and dispensing drugs, including dosage form design |
Pharmacodynamics | What the DRUG does to the body |
Pharmacokinetics | What the BODY does to the drug. Ex, absorption, distribution, metabolism, and elimination |
Pharmacology | The broadest term for the study or science of drugs |
Pharmacotherapeutics | The treatment of pathological conditions through the use of drugs called therapeutics |
Receptor | Molecular structure within or on outer surface of cell. Bind specific substances, cellular effects and drug actions occur here as a result of drug-receptor interaction |
Synergistic effects | Drug interactions in which the effect of a combination of two or more drugs with similar actions are GREATER than the sum of the individual effects of the same drugs given alone |
Therapeutic drug monitoring | The process of measuring drug levels to identify a patient's drug exposure to allow adjustment of dosages with the goals of maximizing therapeutic effects and minimizing toxicity |
Therapeutic effect | The desired or intended effect of a particular medication |
Tolerance | Reduced response to a drug after prolonged use |
Toxicity | The condition of producing adverse bodily effects due to its poisonous qualities |
Trade name | The commercial name given to a drug product by its manufacturer; also called the proprietary name |