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HEPATITIS

Hepatitis

QuestionAnswer
Hepatotropic viruses hepatitis A, B, C, D, and E
Non-hepatotropic viruses Epstein-Barr virus Cytomegalovirus Herpes virus Adenovirus Yellow fever virus
Does not cause chronic hepatitis or a carrier state and only uncommonly causes acute hepatic failure Hepatitis A Virus
___ antibody does not rise until the acute disease is over [HepB] Anti-HBs
The only DNA virus from Hep A to E Hepatitis B
Causes only acute infection Hepatitis A and E
Hepatitis B Serology Antigen and Antibody in ACUTE infection Antigen (+) HBsAg (+) HBeAg HBcAg - not measured (+) HBV DNA Antibody (-) Anti-HBs (+) Anti-HBc [IgM] (+) Anti-HBe
Hepatitis B Serology Antigen and Antibody in WINDOW PERIOD Antigen (-) HBsAg (-) HBeAg HBcAg - not measured (-) HBV DNA Antibody (-) Anti-HBs (+) Anti-HBc [IgM and IgG] (-) Anti-HBe
Viral Hepatitis without a vaccine Hepatitis C and E
A characteristic feature of HEV infection is the high mortality rate among ___, approaching 20% pregnant women
Hepatitis B Serology Antigen and Antibody in RECOVERY phase Antigen (-) HBsAg (-) HBeAg HBcAg - not measured (-) HBV DNA Antibody (+) Anti-HBs (+) Anti-HBc [IgG] (-) Anti-HBe
HepB antigen that signals active replication HBeAg (produced when HBcAg is produced)
HepB antigen that indicates active infection HBsAg
HepB antibody that indicates low transmissibility Anti-HBe
(-) HBsAG (-) Anti-HBc (-) Anti-HBs Susceptible [normal]
(-) HBsAg (+) Anti-HBc (+) Anti-HBs Immune due to natural infection
HepB antibody that indicates previous or ongoing infection Anti-HBc
(-) HBsAg (-) Anti-HBc (+) Anti-HBs Immune due to immunization
(+) HBsAg (+) Anti-HBc (+) IgM (-) Anti-HBs Acute Infection
(+) HBsAg (+) Anti-HBc (-) IgM (-) Anti-HBs Chronic Infection
Antigen (-) HBsAg (-) HBeAg HBcAg - not measured (-) HBV DNA Antibody (+) Anti-HBs (+) Anti-HBc [IgG] Anti-HBe - N/A Recovery Phase of HepB
Hepatitis B Serology Antigen and Antibody in an IMMUNIZED subect Antigen (-) HBsAg (-) HBeAg HBcAg - not measured (-) HBV DNA Antibody (+) Anti-HBs (-) Anti-HBc Anti-HBe - N/A
(+) Anti-HBs inicates? Immunized or Cured
Antigen (+) HBsAg (+) HBeAg HBcAg - not measured (+) HBV DNA Antibody (-) Anti-HBs (+) Anti-HBC [IgG] (-) Anti-HBe Chronic [replicative] HepB
Antigen (+) HBsAg (-) HBeAg HBcAg - not measured (-) HBV DNA Antibody (-) Anti-HBs (+) Anti-HBC [IgG] (+) Anti-HBe Chronic [non-replicative] HepB
(+) Anti-HCV [IgG] (-) HCV RNA [PCR] Cleared HepC Virus
A way to measure fibrosis of the liver for those with hepatitis C. This scoring model is noninvasive, practical, and easy to use. Aspartate aminotransferase to platelet ratio index, or APRI
APRI formula and interpretation [(AST/ULN AST) x 100]/Platelet count lower cutoff: 0.5 - very little to no fibrosis upper cutoff: 1.5 - strong indicator of cirrhosis
Acute Hepatitis D serology (+) HBV (+) HDAg [may also be negative] (+) HDV RNA (+) Anti-HDV [IgM]
Chronic Hepatitis D serology (+) HBV (-) HDAg (+) HDV RNA (+) Anti-HDV [IgG]
Hepatitis A Serology 1. Acute Infection 2. Immunized or Post-exposure 1. (+) HAV RNA (+) IgM 2. (-) HAV RNA (+) IgG
Hepatitis E Serology 1. Acute Infection 2. Post-exposure [Cleared] 1. (+) HEV RNA (+) IgM 2. (-) HEV RNA (+) IgG [2-3 years only]
An acidophilic (eosinophilic / pink-staining on H&E) globule of cells that represents a dying hepatocyte often surrounded by normal parenchyma. Councilman body/Councilman hyaline body/Apoptotic body
HEV + Pregnancy High risk for Fulminant Hepatitis
An area of the medulla oblongata that receives inputs from blood-borne drugs or hormones, and communicates with other structures in the vomiting center to initiate vomiting. [Triggered ng hepatotoxins sa hepatitis] Chemoreceptor trigger zone (CTZ)
Created by: matiNIK
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