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Lymphatic System

Chapter 21

QuestionAnswer
What does the lymphatic system do? Transports and houses lymphocytes and other immune cells that help immune system defend against potentially harmful substances and aids cardiovascular system.
What are the Lymphatic system components? Lymph vessels, lymphatic tissues, and organs
What is lymph? Interstitial fluid that was not reabsorbed by blood capillaries.
What are the components of lypmh? Water, dissolved solutes, and small amount of protein (sometimes cell debris, pathogens, or cancer cells).
How does lymph get into the lymphatic capillaries? Hydrostatic pressure gradient
Where are lymphatic capillaries located? Interspersed around most blood capillaries.
What do lymphatic capillaries have that ensure the entrance of lymph and prevent it from escaping? Flaps
What are lacteals? lymphatic capillaries in GI tract
The wall of lymphatic capillaries are made of what? Overlapping endothelial cells
What holds the lymphatic capillaries to near by strcutures? Anchoring filaments
Lymph flows through vessels in what order? Lymphatic capillaries, lymphatic vessels, lymphatic trunks, and lymphatic ducts
What is Metastasis? Wandering cancerous cells establishing secondary tumors
Lymphatic vessels are fed lymph from? Lymphatic capillaries
Since lymphatic vessels lack a pump to move lymph through, what do they us in order to do so? Skeletal muscle, reparatory pumps, pulsatile movement, rhythmic contraction of smooth muscle
Lymphatic trunks are fed by ? Lymphatic vessels
What do lymphatic vessels have to prevent pooling and backflow? Valves
What are the five lymphatic trunks? • Jugular trunks • Subclavian trunks • Bronchomediastinal trunks • Intestinal trunks • Lumbar trunks
Jugular trunks Drainage of lymph from head and neck
Subclavian trunks Drainage of lymph from upper limbs, breasts, and superficial thoracic wall
Broncho mediastinal trunks Drainage of lymph from deep thoracic structures
Intestinal trunks Drainage of lymph from most abdominal structures
Lumbar trunks Drainage of lymph from lower limbs, abdominopelvic wall, and pelvic organs
Lymphatic ducts are fed by ? Lymphatic trunks
What are the biggest lymphatic vessels? Lymphatic ducts
What does the Right lymphatic duct drain? Upper right quadrant of body
Where does the Right lymphatic duct deliver lymph to? Junction of right subclavian and right internal jugular veins.
What does the Thoracic lymphatic duct drain? Diaphragm to junction of left subclavian and left jugular veins.
Which lymphatic duct is the largest duct? Thoracic lymphatic duct
What does cisterna chyli recieve? Lipid-rich chyle from GI tract.
What is Lymphedema? Accumulation of interstitial fluid due to interference with lymphatic drainage • Extreme cases known as elephantiasis.
What is the function of Primary lymphatic structures? Involved in formation and maturation of lymphocytes
What are some Primary lymphatic structures? Red bone marrow and thymus
What is the function of Secondary lymphatic structures? House lymphocytes and other immune cells.
What are some Secondary lymphatic structures? Spleen, lymph nodes, tonsils, MALT, diffuse lymphatic nodules
Which lymphatic structures is the sites of immune response initiation? Secondary
What does Red Bone Marrow make? T-lymphocytes and B-lymphocytes
Where do T-lymphocytes travel to in order to mature? Thymus
Where is the thymus located? Mediastinum
Is the thymus bigger or smaller in adults compared to children? Smaller
What gradually replaces the thymus over time? Adipose tissue
Trabeculae is located where? Connective tissue capsule
What does Trabeculae do? Subdivides lobes into lobules
The cortex of the thymus contains what type or T-lymphocytes? Immature
The medulla of the thymus contains what type or T-lymphocytes? Mature
What are the Secondary lymphatic structures organized in? Lymphatic organs and aggregates of lymphatic nodules
What are the Secondary lymphatic organs? Spleen and lymph nodes
What are the Secondary lymphatic nodules? Tonsils, MALT, diffuse lymphatic nodules
What do lymphatic nodules do? Filter lymph, remove unwanted substances
What are the 3 lymphatic nodules? • Cervical lymph nodes • Axillary lymph nodes • Inguinal lymph nodes
Cervical lymph nodes receive lymph from where? Head, neck.
Axillary lymph nodes receive lymph from where? Breast, axilla, and upper limb.
Inguinal lymph nodes receive lymph from where? Lower limb and pelvis.
These lymphatic vessels bring lymph into the lymph nodes. Afferent vessels
These lymphatic vessels drain lymph from the lymph nodes. Efferent vessel
What monitored lymph for presence of foreign material when going through lymph nodes? Macrophages, lymphocytes
Lymphoma Enlarged lymph node
What are the two types of Lymphoma? • Hodgkin lymphoma • Non-Hodgkin lymphoma (more common)
What is the largest lymphatic organ? Spleen
Trabeculae in the spleen does what? Divides red and white pulp
What is in White pulp? Clusters of T- and B-lymphocytes and macrophages around central artery
What is in Red pulp? Erythrocytes, platelets, macrophages, and B-lymphocytes.
What does Red pulp store? Erythrocytes and platelets
What are splenic cords? Cells and reticular connective tissue in red pulp
What are splenic sinusoids? Very permeable capillaries in red pulp
What does the spleen filter and monitor? Blood
What is the general flow of blood through spleen? Splenic artery, splenic sinusoid, venules, and splenic vein.
Splenectomy Surgical removal of the spleen
What do Tonsils do? Surveillance inhaled and ingested substances
Tonsillar crypts Invaginations that trap material
What are the three tonsils in the oral cavity? • Pharyngeal tonsil • Palatine tonsils • Lingual tonsils
Where is the Pharyngeal tonsil located? Nasopharynx
What are the Pharyngeal tonsil called when they enlarge? Adenoids
Which tonsil get affected with Tonsillitis? Palatine tonsils
What are signs of Tonsillitis? Fever, chills, sore throat, and difficulty swallowing, tonsil has white spots, back of neck is red
What are Lymphatic nodules? Clusters of lymphatic cells that help defends against infection.
Large structures Lymphatic nodules are called? MALT (Mucosa-associated lymphatic tissue)
Where is MALT located? Gastrointestinal, respiratory, genital, and urinary tracts.
What does MALT do? Help defends against foreign substances.
What is Ileum? MALT in small intestines
What are Peyer patches? Large collections of lymphatic nodules that form bulges in ileum wall.
Lymphatic ducts drain lymph to? Venous circulation
Created by: Olivve
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