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Pulmonary Vent
| Question | Answer |
|---|---|
| surfactant | reduces surface tension of alveolar fluid that locks shape in place, produced by type II alveolar cells |
| physical factors influencing pulmonary ventilation | air way resistance, alveolar surface tension, lung compliance; they affect the ease of air passage and amount of energy required for ventilation |
| tidal volume (TV) | amount of air moved into and out of lungs with each breath, averages -500ml |
| inspiration | gases flow into lungs |
| inspiration | chest expands, diaphragm contracts, lungs stretch |
| expiration | gases exit lungs |
| expiration | chest contracts, diaphragm relaxes |
| expiration | volume decreases pressure increases |
| inspiration | volume increases pressure decreases |
| atmospheric pressure (Patm) | pressure exerted by air surrounding the body, 760mm Hg at sea level=1atm |
| intrapulmonary pressure (Ppul) | intra-alveolar pressure, fluctuates with breathing, always equalizes with Patm |
| rule 1 | volume changes lead to pressure changes, p increases V decreases= p decreases v increases |
| rule 2 | pressure changes allow flow of gases to equalize pressure |
| Boyle's law | relationship between pressure and volume of a gas, pressure varies inversely with volume |
| quiet inspiration | active process involving inspiratory muscles |
| quiet inspiration | diaphragm contracts, external intercostals contract |
| result of quiet inspiration | in thoracic cavity and intrapulmonary pressure drops by 1mm Hg (Ppul←Patm) and air flows into lungs down pressure gradient until intrapulmonary pressure is 0 |
| forced deep inspiration | active process from vigorous exercise or COPD and accessory muscles activated |
| forced deep inspiration | external intercostals contract, diaphragm contracts |
| result of forced deep inspiration | all act s to further increase thoracic cage size, creating a larger pressure gradient so more air flows into lungs |
| quiet expiration | passive process in heath individuals |
| quiet expiration | inspiratory muscles relax, diaphragm relaxes, external intercostals relax |
| result of quiet expiration | thoracic cavity volume decreases then lungs recoil, volume decreases causing intrapulmonary pressure to increase by +1mm Hg (Ppul→Patm), air exits lungs |
| forced deep expiration | active process accessory muscles are activated |
| forced deep expiration | internal intercostals contract, obliques contract, transverse abdominal contracts |
| result of forced deep expiration | lungs empty more air than normal and decreases thoracic volume |
| airways resistance | size of airways |
| alveolar surface tension | with or without surfactant |
| lung compliance | measure of change in lung volume that occurs with given change in transpulmonary pressure, stretchiness |