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Embryology

UWORLD Round 1 2021

QuestionAnswer
What is connected by the Ureteropelvic junction? Kidney and the Ureter
Connection site below the kidney and the ureter Ureteropelvic junction
What is the most common cause of Unilateral Fetal Hydronephrosis? Inadequate canalization of the ureteropelvic junction (UPJ).
What is the MC consequence of inadequate canalization of Ureteropelvic junction? Unilateral Fetal Hydronephrosis
What is the most common cause of Bilateral fetal hydronephrosis? Posterior Urethral valves
What is a consequence of Posterior Urethral valves in boys? Bilateral Fetal Hydronephrosis
Herniation of the abdominal contents into the thorax Congenital Diaphragmatic hernia
What happens to the lungs in newborn with Congenital Diaphragmatic hernia? Pulmonary hypoplasia due to compression of the lungs
What are chest X-ray findings in Congenital Diaphragmatic hernia? 1. Thoracic Bowel loops 2. Distal endo the feeding tube may also be seen within the thorax
What is Annular Pancreas? Pancreatic tissue encircling the descending duodenum, is caused by failure of the Ventral Pancreatic bud, to properly migrate and fuse with the dorsal bud during the 7th and 8th weeks of fetal development
Which pancreatic bud fails to migrate and fuse leading to Annular Pncrases? Ventral Pancreatic bud
What are the symptoms seen in Annular Pancreas? Duodenal obstruction or Pancreatitis
What weeks of gestation are the ones involved in development of Annular Pancreas? 7th and 8th weeks
What is commonly found inside a Meckel diverticulum? A number of ECTOPIC tissues; most commonly gastric epithelium
What is the most common ectopic tissue found inside a Meckel diverticulum? Gastric epithelium
What is a common consequence of increased Gastric Acid production? Ulceration and subsequent bleeding
What are the main symptoms of Meckel diverticulum? 1. Painless melena 2. Diverticulum gets inflamed and presents like an acute appendicitis
Why is Meckel diverticulum often mistaken by acute appendicitis? Due to diverticulum inflammation
What gives rise to Intestinal Malrotation? Results when the midgut undergoes incomplete embryological counterclockwise rotation
What condition is due to the incomplete embryological counterclockwise rotation of the midgut? Intestinal malrotation
What are the main symptoms of Intestinal Malrotation? 1. Intestinal obstruction, due to compression by the adhesive bands 2. Midgut volvulus, due to intestinal ischemia due to twisting around the blood vessels
What are Ladd's (fibrous) bands? Fibrous bands that connect the retroperitoneum in the RLQ to the Right Colon/Cecum by passing the 2nd part of the duodenum
What conditions is often seen with Ladd's bands? Intestinal malrotation
What type of vomiting is seen with Intestinal malrotation? Bilious vomiting during the fists days of life
Is Intestinal malrotation a problem of the midgut, hindgut, or foregut? Midgut
Is bilious or non-bilious vomit associated with Intestinal malrotation? Bilious vomit
What is a "diverticulum"? A single pouch of the digestive tract
What is the result of incomplete fusion of Urethral (urogenital) folds in males? Hypospadias
What causes hypospadias? Incomplete fusion of the urethral folds
What is Hypospadias? Abnormal opening of the urethral proximal to the glans penis along the ventral shaft of the penis
What is Polyhydramnios? Excessive accumulation of amniotic fluid
How is Polyhydramnios presented? Increased abdomen circumference out of proportion to gestational age
What causes Polyhydramnios? Decreased fetal swallowing or increased fetal urination
What condition is due to decreased fetal swallowing or increased fetal urination? Polyhydramnios
What are fetal anomalies associated to polyhydramnios due to decreased fetal swallowing? GI obstruction and Anencephaly
Intestinal atresias are often the result of: GI obstruction due to polyhydramnios caused by impaired fetal swallowing
What is the role of Paramesonephric ducts in female embryology? Paramesonephric duct fuse to form the Fallopian tubes, cervix, uterus, and upper vagina
What is formed in females by the fusion of the Paramesonephric ducts? Fallopian tubes, uterus, cervix, and upper vagina
What are consequences of failure or disruption in female embryogenic Paramesonephric duct fusion? Mullerian tract anomalies an renal anomalies
What is the the result of incomplete lateral fusion of the Paramesonephric ducts in females? Bicornuate uterus
What is the cause of Bicornuate uterus? The incomplete LATERAL fusion of the Paramesonephric ducts
How is Bicornuate uterus characterized visually? It is seen with an indentation in the center of the fundus
What is a common embryological cause of recurrent miscarriages? Bicornuate uterus
What parts of the Pancreas are formed by the Dorsal Pancreatic bud? Majority of pancreatic tissue (body, tail, and most of head)
What is formed by the Ventral Pancreatic bud? Uncinate process, inferior/posterior part of the pancreatic head, and major pancreatic duct (of Wirsung)
What is the major pancreatic duct? Duct of Wirsung
What pancreatic bud, ventral or dorsal, gives rise to the the major pancreatic duct (of Wirsung)? Ventral pancreatic bud
What pancreatic bud gives rise the the tail, body, and most of the pancreatic head? Dorsal pancreatic bud
How is the thyroid gland formed? Evagination of the Pharyngeal epithelium and descens to the lower neck
What can lead to the presence of Ectopic thyroid tissue? Failure of migration, the thyroid can reside anywhere along the thyroglossal duct's usual path, including the tongue
Ectopic thyroid tissue in the tongue is known as: Lingual thyroid
The presence of Lingual thyroid is due to a defect of : Failure of migration
What gives rise the evagination of pharyngeal epithelium and decent to the lower neck? Thyroid gland
Why is the Pierce Robin classified as a sequence? Because the primary defect leads to a cascade of further malformations
What is the primary defect of the Pierre Robin sequence? Hypoplasia of the mandibular prominence
Hypoplasia of the mandibular prominence is often associated with: Pierre Robin sequence primary defect
What are the secondary defects in Pierre Robin sequence? Micrognathia, posteriorly displaced tongue, and U-shaped cleft palate
What condition is often associated with a U-shaped cleft palate, posteriorly displaced tongue,and small mandibular prominence? Pierre Robin sequence
Created by: rakomi
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