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Biochemistry

Rate Limiting Enzymes

QuestionAnswer
Glycolysis Phosphofructokinase-1
Glycogenesis Glycogen synthetase (Dephosphorylated form)
Glycogenolysis Phosphorylase
Gluconeogenesis 1. Pyruvate carboxylase 2. Phosphoenolpyruvate carboxykinase (PEP-C)
HMP shunt Glucose-6-phosphate dehydrogenase (G6PD)
TCA cycle Isocitrate dehydrogenase
Urea synthesis CPS-I Carbamoyl phosphate synthetase, or , Ornithine transcarbamoylase
Fatty acid synthesis Acetyl CoA carboxylase
Cholesterol synthesis HMG CoA reductase
Ketone bodies synthesis HMG CoA synthetase
Fatty acid oxidation Carnitine acyltransferase-1
Purine synthesis Phosphoridosyl pyrophosphate synthetase (PRPP synthetase)
Uric acid synthesis Xanthine oxidase
Porphyrin synthesis d-ALA synthetase
Bile acid synthesis 7-a-hydroxylase
Created by: rakomi
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