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3rd module

Terms

Innate something we are naturally born with/ works on many different
Adaptive something we have learned/ works on only one
Innate immunity line of defenses 1st and 2nd lines
Adaptive immunity line of defense 3rd line
Antimicrobial peptides small peptide fragments that can kill bacteria by making pores in cell membranes
Peristalsis moves "things" so microbes cant "stick around"
Normal microbiota microoganisms that normally reside on or in healthy individual (ex: urogenital tract - lactobacillus species)
Types of cells in blood erythrocytes, thrombocytes & leukocytes
2ns line defense cells neutrophils, monocytes/macrophages & dendritic cells
Vasodilation widens blood vessels which increases blood flow
5 signs of inflammation redness, heat, pain, loss of function & swelling
Diapedesis phagocytes squeeze between endothelial cells
Margination getting phagocytes to stop and stick to the inner lining of the blood vessel walls
important antimicrobial substance associated with secondary host defenses? complement system (complements immune cells in destroying pathogens)
where complement proteins found? circulating in blood
how is complement system activated? occurs through antibody-antigen reactions or the presence of a pathogen
how can complement system destroy invading microbes? 1. enhancing phagocytosis 2. initiating inflammation 3. promoting cytolysis
what can a lymphocyte stem cell become? can become either a B cell or T cell
B cell differentiate where? & T cell too? B = bone marrow, T = thymus
Where do B and T cell migrate to? Spleen and lymph nodes
role of lymphatic system? transport lymphocytes to "filter system" against invading pathogens
what is an epitope? a LARGE antigen that has many smaller, exposed regions antigen-binding sites of antibody are SPECIFIC only bind to particular epitope
why are B cell antigen presenting cells? What else is also considered a antigen presenting cell? B cells present foreign antigen fragments on their surface A macrophage.
What can activated B cell become? a plasma B cell or memory B cell Plasma B cell capable of secreting antibodies
Natural active immunity getting sick and getting better
Natural passive immunity from mom before and after birth
Artificial active immunity EX: vaccination
Artificial passive immunity EX: infusion/immunotherapy
Created by: cindysaldivar
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