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Musculoskeletal
FA review Round 1 2020
| Question | Answer |
|---|---|
| What are the two main characteristics of Rubella unvaccinated patients? | Maculopapular rash and Postauricular lymphadenopathy |
| What was the previous name of Rubella? | German (3-day) measles |
| Important Togavirus | Rubella |
| Common injectable drug used for Rheumatoid arthritis: | Etanercept |
| What is the MOA of Etanercept? | Block TNF-alpha binding |
| What is used to treat acute inflammation? | Steroids |
| What are common complications of Mumps? | Parotiditis, Orquitis, Pancreatitis, and Meningitis |
| How is Pancreatitis expressed in a patient with Mumps? | Epigastric pain |
| What is the Cremasteric reflex? | Testicular lift is elicited by stroking the inner thigh |
| What condition is seen with an absent Cremasteric reflex? | Testicular torsion |
| What is an important reflex lost in Testicular torsion? | Cresmatic reflex |
| Which muscle is stimulated in Cremasteric reflex? | Internal Oblique Abdominal muscle |
| Stimulation of Internal Oblique abdominal muscle causes --> | Cresmatic reflex |
| What is the sensory supply of Ulnar nerve? | Over the medial 1 1/2 digits and hypothenar eminence |
| Which nerve provides sensation to the medial 1 1/2 digits of the hand? | Ulnar nerve |
| The ulnar nerve supplies sensory information of the Thenar or Hypothenar eminence? | Hypothenar |
| What is the motor innervation of the Ulnar nerve? | Deep motor branch that supplies most of the intrinsic muscles of the hand, including the ADDUCTOR Pollicis muscle |
| Which important hand muscle is innervated by the Ulnar nerve? | Adductor pollicis |
| What is a significant symptom of Polymyalgia rheumatica? | Morning stiffness in the shoulders |
| Which conditions associated with Giant-cell arteritis? | Polymyalgia rheumatica |
| Is Polymyalgia rheumatica associated with muscle weakness? | No; it does not cause muscle weakness |
| What is the main treatment for GCA? | Prednisone |
| What is the mode of inheritance of Duchenne Muscular Dystrophy? | X-linked recessive pattern |
| What are the clinical features of DMD? | Bulging, fatty calf muscles manifesting in early childhood |
| Which autoimmune condition is due to a microtubule dysfunction? | Chediak-Higashi syndrome |
| What is caused of Chediak-Higashi syndrome? | Abnormal cellular trafficking, which results in failure of phagolysosome formation |
| Common symptoms of Chediak-Higashi syndrome? | Progressive neurodegeneration, lymphohistiocytosis, albinism, pyogenic infections, peripheral neuropathy, and bleeding tendencies |
| What is lymphohistiocytosis? | Rare but potentially fatal condition of normal but overactive histiocytes and lymphocytes that commonly appears in infancy |
| What is the main type treatments for Staph aureus infection? | 1. Oral dicloxacillin, 2. IV nafcillin/oxacillin |
| How does Tacrolimus? | Inhibits calcineurin by complexing with FK-binding protein 12 |
| Important Calcineurin inhibitor by binding to FK-binding protein 12. | Tacrolimus |