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Cell Exam 2
exam 2
| Question | Answer |
|---|---|
| The turnover number for an enzyme is derived directly from the value of the Km. | False |
| Transerve movement of lipids in a membrane is much more common and rapid than lateral movement of lipids in a membrane. | False |
| Even though the exact amount of proteins and the exact amount of lipids w/in a membrane can vary, the ratio of protein to lipid is always the same. | False |
| The ABO blood grouping molecules are glycolipids. | True |
| Sphingomyelin is a type of sterol. | False |
| Most glycolipids are sphingosine based, not glyceral based. | True |
| Sterols (like cholesterol), are found in the membranes of most prokaryotic cells. | False |
| The Na+/K+ pump is an example of a P-type ATPase | True |
| Some G-proteins are trimeric, some G-proteins are pentameric | False |
| The membrane of the TGN is a thicker membrane than the CGN | True |
| Growth factors are more likely to interact with G-protein receptors rather than kinase receptors | False |
| Phospholipid synthesis occurs on the cytoplasmic side of the SER membrane bilayer | True |
| The RER is more tube-like, the SER is more sac-like | False |
| Lipid anchored proteins are difficult to remove from a membrane and would require detergents or oganic solvents to so do | True |
| Animal fats are more highly saturated than plant fats | True |
| The size limit for molecules that could potentially move across a membrane by simple diffusion is around 1000 daltons, i.e. anything less than 1000 daltons can pass through by simple diffusion (nonpolar and not charged) | False |
| The marker enzyme for the SER? | Glucose-6-phosphate |
| In the G-protein receptor mechanism, what has to be bound to the G-protein to turn it "off"? | GDP |
| An activated G protein can turn on this enzyme resulting in higher levels of cAMP w/in the cell | Adenylyl cyclose |
| cAMP is a 2nd messenger that commonly functions by activating this enzyme | protein kinase A |
| In N-linked glycosylation, sugar is added to amine group of the amino acid __? | Asparagine |
| The term that applies to both the layers/folds of he RER and the layers/folds of the Golgi | cisternae |
| This 2nd messenger causes the release of calcium ion from intracellular stores | insitol trisphosphate |
| These vesicles are involved witht the transport of proteins from one layer of the Golgi complex to the next | shuttle vesicles |
| What is the targeting signal for hydrolytic enzymes destined for lysosomes? | mannose-6-phosphate |
| This term refers to the general directional flow of materials and vesicles from the RER to the Golgi and out of the cell | Anterograde |
| __ endosomes are the immediate precursors to lysosomes. | Late |
| The type of enocytosis where solid structure >0.5um are taken into the cell | Phagocytosis |
| The SER contains enzymes that are __ toxic substances increasing thier solubility making it more probable that the toxic substance will then get secreted in the urine. | Hydroxylate |
| this type of lysosome is specialized in digesting internal self cellular components | Autophagic |
| Requires an integral membrane protein | Active Transport Facilitated Diffusion |
| Doubling the concentration of the molecule to be transported will double the rate of transport (linear relationship) | Simple Diffusion |
| Osmosis | Simple Diffusion |
| GLUT1 | Facilitated Diffusion |
| Sodium entering an intestinal cell from the intestinal lumen | Facilitated Diffusion |
| Requires Energy | Active transport |
| Glucose entering an intestinal cell from the intestinal lumen | Facilitated Diffusion |
| Movement from a high concentration to low concentration | Simple Diffusion Facilitated Diffusion |
| The Na+/K+ pump | Active Transport |
| Ions will not enter or leave a cell by this mechanism | Simple Diffusion |