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microbiology
innate immunity
| Question | Answer | |
|---|---|---|
| progenitor cells are (n) | hematopoietic stem cells | small number of cells with characteristic cell surface markers ; present throught the life of the person |
| how is somatic cell division different from stem cell differentiation | stem cells after division result in a differentiated cell and stem cell | |
| • Stem cells and other cells in the bone marrow are influenced by (n) | stromal cells | stromal cells secrete growth factors or display molecules on their cell surface |
| hematopoietic stem cells give rise to | pluripotent stem cells that are either a myeloid progenitor cell or lymphoid progenitor cells | |
| • Myeloid progenitors give rise to | red blood cells, platelets, basophils, eosinophils, neutrophils or monocytes/macrophages. | |
| • Lymphoid progenitors give rise to | B cells, T cells and natural killer (NK) cells. | |
| inflammation is associated with what kind of immune system ( adaptive / innate) | innate | |
| list 5 attributes of innate immunity (n) | primitive , first line , involved in pattern recognition , necessary for adaptive , no memory | primitive -- evolutionarily older |
| list 5 attributes of adaptive ( acquired) immunity | recent , activated , specific epitope recognition , improved response by repeated infection , had memory | |
| Cytokines produced as a consequence of adaptive immunity (e.g., interferon-gamma (IFN-g) can act on | macrophages (cells of the innate immune system) to cause them to become more microbicidal (“classical activation”) | |
| Cytokines produced during the innate immune response can affect | the type of adaptive immune response (e.g., IL-4 favors the development of a humoral Th2 antibody response) | |
| Defensins are found in | neutrophils and macrophage | |
| Defensins are produced | by Paneth cells in intestinal crypts; | |
| defensins are thought to act by | inserting directly into organism and creating a pore in the microbial membrane that leads to osmotic rupture of microbe | |
| Immunological defense in the mouth is mediated by | a complex system of cells and molecules. | |
| Cells involved in host defense in the oral cavity include | the mucosal barrier epithelium and phagocytes, lymphocytes, and other leukocytes involved in inflammation and adaptive immunity. | |
| Membranolytic activity is Found in | myeloid cells (neutrophils and macrophages) and on mucosal surfaces | |
| what are the innate immune defenses in the oral cavity | Mucosal barrier and saliva | |
| mucosal barrier includes ; | epithelial cells, epithelial antimicrobial peptides , mucins , oral microbiota | |
| Cells of the immune system originate form(n) | stem cells present in bone marrow | bone marrow found in long bones and pelvis contain both progenitor cells and mature cell types |
Created by:
jemalk
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