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Rapid Review FA
Classic Presentations Page 3
Question | Answer |
---|---|
Painless erythematous lesions on palms and soles | Janeway lesions (infective endocarditis, septic emboli/ microabscesses) |
Splinter hemorrhages in fingernails | Bacterial endocarditis |
Retinal hemorrhages with pale centers | Roth spots (bacterial endocarditis) |
Distant heart sounds, distended neck veins, hypotension | Beck triad of cardiac tamponade |
Cervical lymphadenopathy, desquamating rash, coronary aneurysms, red conjunctivae and tongue, hand-foot changes | Kawasaki disease (mucocutaneous lymph node syndrome, treat with IVIG and aspirin) |
Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria | Immunoglobulin A vasculitis (Henoch-Schönlein purpura, affects skin and kidneys) |
Telangiectasias, recurrent epistaxis, skin discoloration, arteriovenous malformations, GI bleeding, hematuria | Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) |
Skin hyperpigmentation, hypotension, fatigue | 1° adrenocortical insufficiency ACTH,α-MSH (eg, Addison disease) |
Cutaneous flushing, diarrhea, bronchospasm | Carcinoid syndrome (right-sided cardiac valvular lesions, increase 5-HIAA) |
Cold intolerance, weight gain, brittle hair | Hypothyroidism |
Cutaneous/dermal edema due to deposition of mucopolysaccharides in connective tissue | Myxedema (caused by hypothyroidism, Graves disease [pretibial]) |
Facial muscle spasm upon tapping | Chvostek sign (hypocalcemia) |
No lactation postpartum, absent menstruation, cold intolerance | Sheehan syndrome (postpartum hemorrhage leading to pituitary infarction) |
Deep, labored breathing/hyperventilation | Diabetic ketoacidosis (Kussmaul respirations) |
Pancreatic, pituitary, parathyroid tumors | MEN 1 (autosomal dominant) |
Thyroid tumors, pheochromocytoma, ganglioneuromatosis, Marfanoid habitus | MEN 2B (autosomal dominant RET mutation) |
Thyroid and parathyroid tumors, pheochromocytoma | MEN 2A (autosomal dominant RET mutation) |
Jaundice, palpable distended non-tender gallbladder | Courvoisier sign (distal malignant obstruction of biliary tree) |
Vomiting blood following gastroesophageal lacerations | Mallory-Weiss syndrome (alcoholic and bulimic patients) |
Dysphagia (esophageal webs), glossitis, iron deficiency anemia | Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma) |
Enlarged, hard left supraclavicular node | Virchow node (abdominal metastasis) |
Arthralgias, adenopathy, cardiac and neurological symptoms, diarrhea | Whipple disease (Tropheryma whipplei) |
Severe RLQ pain with palpation of LLQ | Rovsing sign (acute appendicitis) |
Severe RLQ pain with deep tenderness | McBurney sign (acute appendicitis) |
Hamartomatous GI polyps, hyperpigmented macules on mouth, feet, hands, genitalia | Peutz-Jeghers syndrome (inherited, benign polyposis can cause bowel obstruction;cancer risk, mainly GI) |
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth | Gardner syndrome (subtype of FAP) |
Abdominal pain, ascites, hepatomegaly | Budd-Chiari syndrome (posthepatic venous thrombosis) |