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Rapid Review FA

Classic Presentations Page 3

QuestionAnswer
Painless erythematous lesions on palms and soles Janeway lesions (infective endocarditis, septic emboli/ microabscesses)
Splinter hemorrhages in fingernails Bacterial endocarditis
Retinal hemorrhages with pale centers Roth spots (bacterial endocarditis)
Distant heart sounds, distended neck veins, hypotension Beck triad of cardiac tamponade
Cervical lymphadenopathy, desquamating rash, coronary aneurysms, red conjunctivae and tongue, hand-foot changes Kawasaki disease (mucocutaneous lymph node syndrome, treat with IVIG and aspirin)
Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria Immunoglobulin A vasculitis (Henoch-Schönlein purpura, affects skin and kidneys)
Telangiectasias, recurrent epistaxis, skin discoloration, arteriovenous malformations, GI bleeding, hematuria Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome)
Skin hyperpigmentation, hypotension, fatigue 1° adrenocortical insufficiencyŽ ACTH,α-MSH (eg, Addison disease)
Cutaneous flushing, diarrhea, bronchospasm Carcinoid syndrome (right-sided cardiac valvular lesions, increase 5-HIAA)
Cold intolerance, weight gain, brittle hair Hypothyroidism
Cutaneous/dermal edema due to deposition of mucopolysaccharides in connective tissue Myxedema (caused by hypothyroidism, Graves disease [pretibial])
Facial muscle spasm upon tapping Chvostek sign (hypocalcemia)
No lactation postpartum, absent menstruation, cold intolerance Sheehan syndrome (postpartum hemorrhage leading to pituitary infarction)
Deep, labored breathing/hyperventilation Diabetic ketoacidosis (Kussmaul respirations)
Pancreatic, pituitary, parathyroid tumors MEN 1 (autosomal dominant)
Thyroid tumors, pheochromocytoma, ganglioneuromatosis, Marfanoid habitus MEN 2B (autosomal dominant RET mutation)
Thyroid and parathyroid tumors, pheochromocytoma MEN 2A (autosomal dominant RET mutation)
Jaundice, palpable distended non-tender gallbladder Courvoisier sign (distal malignant obstruction of biliary tree)
Vomiting blood following gastroesophageal lacerations Mallory-Weiss syndrome (alcoholic and bulimic patients)
Dysphagia (esophageal webs), glossitis, iron deficiency anemia Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma)
Enlarged, hard left supraclavicular node Virchow node (abdominal metastasis)
Arthralgias, adenopathy, cardiac and neurological symptoms, diarrhea Whipple disease (Tropheryma whipplei)
Severe RLQ pain with palpation of LLQ Rovsing sign (acute appendicitis)
Severe RLQ pain with deep tenderness McBurney sign (acute appendicitis)
Hamartomatous GI polyps, hyperpigmented macules on mouth, feet, hands, genitalia Peutz-Jeghers syndrome (inherited, benign polyposis can cause bowel obstruction;cancer risk, mainly GI)
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth Gardner syndrome (subtype of FAP)
Abdominal pain, ascites, hepatomegaly Budd-Chiari syndrome (posthepatic venous thrombosis)
Created by: cleomp
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