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213 - LA3 (T)
Haematological System
| Question | Answer |
|---|---|
| polycythemia - what is it and s/s | too many RBCs = increased blood viscosity, hypervolemia impaired circulation, splenohepatomegaly |
| What is thrombocytopenia and s/s | destruction of platelets by immune system s/s - increased bleeding |
| What is the opposite of thrombocytopenia? | Thrombocytosis - excessive platelets |
| Hemochromatosis | "iron overload" - increased intestinal iron absorption/increased deposit into tissues |
| 3 types of hemophilia | A - factor VIII deficiency B - factor IX deficiency (Christmas Disease) Von Willebrands (deficient von willebrand coagulation protein) |
| what are you lacking in pernicious anemia | intrinsic factor (which is required for Vit b12 absorption) |
| What is Thalessemia | genetic - inadequate production of Hgb |
| Lifespan of RBC's in sickle cell anemia VS lifespan of normal RBC's | 10-20 days vs 120 days |
| Nursing Management of Sickle Cell | *pain management, oxygen, fluids. sometimes blood transfusions |
| hemolytic anemia | recipient's antibodies destroy donor RBC's |
| aplastic anemia | pancytopenia, hypocellular bone marrow (impaired production of cells in bone marrow) |
| Which type of leukemia is common in children | ALL acute lymphocytic leukemia |
| S/S of leukemia | All relate to bone marrow failure + organ infiltration (fever, infection, pallor, weakness, fatigue, palpitations, abd. pain, confusion, headaches, ecchymosis/petichiae from thrombocytopenia |
| Difference between hodgkins and non-hodgkins lymphomas? | Hodgkins: reed sternberg cells Non-Hodgkins: arises from B and T cells - NO reed sternberg cells |
| What is multiple myeloma - caridinal s/s? | cancer of plasma cells in bone marrow. infiltrates into bone tissue/organs. cardinal s/s - pathological fractures |
| 4 phases of chemotherapy | 1. Induction - aggressive start, pt quite ill (if remission is accomplished --> #2 if not repeat #1) 2. Intensification - same drugs, higher dosage 3. Consolidation - ensures all leukemic cells are eradicated from body 4. Maintenance |