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EXAM 1

Drugs Affecting the Autonomic Nervous System

QuestionAnswer
Parasympathetic Nerves "Rest and Digest"
Sympathetic Nerves "Fight or Flight"
Parasympathetic nerves are also known as..... Cholinergic (Muscarinic Agonist), Parasympathomimetic, Cholinomimetic
Sympathetic Nerves are also known as... Adrenergic (Adrenergic Agonist) , Sympathomimetic, Catecholamines (dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline)
Parasympathetic Nerves Effects Constrict pupils (miosis) Stimulate saliva-Increased saliva Slow heart beat- decreased HR and AV conduction, slight decrease in contractility Constrict airways (bronchoconstriction)
Parasympathetic Nerves Effects Continue.... Stimulate activity of intestines (diarrhea)- Increased gastrointestinal mucous Contract bladder (makes you urinate)-Bladder fundus contraction Relaxation of Urinary Sphincter Promote erection of genitals Acetylcholine released
Sympathetic Nerves Effects Dry mouth- inhibit salivation Dilated pupils (mydriasis) Increased contractility (Heart) Increased heart rate and AV conduction Bronchodilation- relax airways Bladder fundus relaxes, sphincter contracts Inhibit activity of stomach
Sympathetic Nerves Effects Continue... Vasoconstriction Stimulate release of glucose; inhibit gallbladder Inhibit activity of intestines (constipation) Secrete epinephrine and norephinephrine Relax bladder and contraction of urinary sphincter Promote ejaculation and vaginal contraction
Adrenergic (Post-synaptic) Receptor Stimulation- Alpha Receptors Alpha1 receptors: vasoconstriction, mydriasis, GI/ bladder sphincter contraction Alpha2 receptors: vasodilation (lower BP)
Adrenergic (Post-synaptic) Receptor Stimulation- Beta Receptors Beta1 receptors: cardiac stimulation (increase heart rate, contractility) Beta2 receptors: bronchodilation, vasodilation, GI relaxation, uterine relaxation, glycogenolysis (hyperglycemia)
Uses of Adrenergic Drugs Mydriasis (dilate eyes for eye exam) Cause bronchodilation and manage anaphylactic shock Improve myocardial contractility, increase in heart rate and blood pressure Decrease peristalsis Increases blood sugar Prolong local anesthetics
Created by: 2850009458368456
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