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ANS receptors
Receptors | Location | Effects |
---|---|---|
Alpha 1 receptors | Blood vessels - vaso constriction Eye -mydriasis | Vasoconstriction |
Alpha 2 receptors | Negative feedback inhibition of norepinephrine release Pancreas - inhibits insulin release | Vasodilation |
Beta 1 receptors | Heart - increases heart rate and contractility Kidney - stimulate renin release from jg apparatus - increase BP | Increase HR |
Beta 2 receptors | Lung - bronchodilation Liver and muscle - vasodilation GI - decrease motility Bladder - relaxation | Vasodilation |
Nm receptors | NMJ | Act by ligand gated receptors sodium/potassium |
Nn | Adrenal medulla Autonomic ganglia | Act by ligand gated receptors - calcium / sodium / potassium |
M1 | Stomach CNS | Act by IP3/DAG - Gq |
M2 | Heart Bronchus | K+ opening - cAMP / Gi |
M3 | Glands, eye,bladder,gut | IP3/DAG / Gq |