click below
click below
Normal Size Small Size show me how
Vent System & CSF Ob
Question | Answer |
---|---|
lateral ventricles - describe and relationship to surrounding brain structures | two, not on midline, around corpus colosseum, septum pellucidum, anterior horn body, posterior horn inferior horn inter-ventricular foramen atrium (trigone) |
third ventricle - describe and relationship to surrounding brain structures | middle of lateral ventricles, posterior and connected to top part of lateral ventricle, more medial |
fourth ventricle - describe and relationship to surrounding brain structures | below the third ventricle, connected by connected by mesencephalic aquaduct |
microscopic anatomy of choroid plexus - layers where substances pass the vascular space and enter CSF | roof of each ventricle, made of choroid epithelium, small amounts of connective tissue and capillaries, are fenestrated/leaky, choriod epithelium is united by tight junctions and separates capillaries from CSF in ventricles, majority of CSF produced here |
anatomy of blood CSF barrier. Function? | tight junctions between choroid epithelial cells, protects CSF from materials found in blood that are harmful to CSF |
circulation of CSF from origin to reabsorption | made at choroid plexus, circulates through ventricles & central canal, through subarachnoid space via lateral & median apertures of 4th v and around spinal cord and brain, gets reabsorbed with venous blood at arachnoid granulations |
anatomy and function of arachnoid villi/granulations | tufts of arachnoid, protrudes through dura and into dural sinus, villi~grannulation, many in superior sagittal sinus, 1 way valve from subarachnoid space to sinus, pressure dependent function, CSF absortion is passive, one way, |
hydrocephalus | high volume of CSF in ventricles, cased by increased production or lowered reabsorption, BIGGEST cause is blockage of circulation |
ventricular system | CSF, fluid filled system in brain, 4 ventricles in brain and continuous with central canal of spinal cord, continuous with subarachnoid space in 4th ventricle in medulla |
CSF production | NOT influenced by blood pressure OR pressure of CSF in the ventricles (is influenced by somatic pressure of blood but this isn't as important) |
CSF absortion at arachnoid granulations | passive process, dependent on pressure gradient, one way process (CSF > venous) |
BBB | endothelium (capilaries) does tight junctions with astrocytes |
B CSF B | choroid epithelium does the work |
BBB vs BCSFB | endothelium vs choroid plexus, choroid plexus is active while arachnoid granulations is passive |