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Cerebrovas System Ob
| Question | Answer |
|---|---|
| What arteries make up the internal carotid system, and what general parts of the brain does it supply? | internal carotid a., posterior communicating a., middle cerebral a (M1 & M2 segments of middle cerebral a.) lenticulostriate aa., anterior cerebral a., anterior communicating a. |
| What arteries make up the vertebrobasilar system, and what general parts of the brain does it supply? | vertebral a., posterior spinal a., anterior spinal a, posterior inferior cerebellar a., basilar a., anterior inferior cerebellar a., pontine aa., superior cerebellar a., posterior cerebral a. |
| Identify by name the major cortical branches and be able to indicate the areas of the cerebral cortex that each supplies. | anterior cerebral a, middle cerebral a, posterior cerebral a |
| Describe the origin of the major arteries that supply the spinal cord. Indicate in spinal cord cross section the regions of the cord supplied by its arteries. | anterior spinal artery, posterior spinal aa |
| Describe the cellular anatomy and function of the blood-brain barrier and the blood-CSF barrier. Be sure to be able to say how these two barriers are similar and how they are different | physiologic barrier between intravascular space & CNS ECF, astrocytes have end feet that release chemical signals to make ENDOTHELIAL CELLs not leaky (tight junction), small molecules, gases, substances with specific transporters, lipid soluble substances |
| Describe intracranial bleeding in terms of real and potential spaces. | epidural bleed vs subdural bleed, herniations |
| posterior communicating a. | connects internal carotid a. with vertebral basilar system |
| internal carotid a | ( most of the anterior potion of the cerebrum) |
| posterior communicating a | connects internal carotid a. with vertebral basilar system |
| middle cerebral a | lateral surface cerebral hemispheres to parieto-occipital sulcus; rostromedial temporal lobe; insular cortex M1 & M2 segments of middle cerebral a. |
| lenticuostriate aa | (diencephalon, internal capsule, basal nuclei) |
| anterior cerebral a | medial surface cerebral hemispheres to parieto-occipital sulcus |
| anterior communicating a. | (distributes blood to portions of the ventromedial frontal lobes (including parts of the orbitofrontal lobes) and related structures) |
| vertebral a | (supplying component of the vertebrobasilar vascular system, supply blood to the upper spinal cord, brainstem, cerebellum, and posterior part of brain) |
| posterior spinal a | posterior spinal cord |
| anterior spinal a | anterior spinal cord, grey matter, central branches |
| posterior inferior cerebellar a | medulla, cerebellum |
| basilar | ( cerebellum, brainstem, and occipital lobes) |
| anterior inferior cerebellar a | pons, cerebellum |
| pontine aa | (pons) |
| superior cerebellar a | midbrain, cerebellum |
| posterior cerebral a | inferior & medial surfaces of temporal, occipital lobes to parieto-occipital sulcus |
| cerebral arterial circle | cortical branches 3 pairs, also known as circle of willis |
| the blood brain barrier | physiologic barrier between intravascular space (blood inside vessles) and CNS ECF, we don't want blood to have free access, found in brain and spinal cord |
| why do we have the BBB | not everying in blood is good for neurons, protects |
| endothelial cells (endothelium) | single layer of cells, capillaries are leaky allowing for good stuff to go to cells and bad stuff gets carried away |
| astrocyte end feet | attaches astrocytes to endothelia cells, induce formation of tight junction, chemical signals make the endothelia cells not leaky and tight |
| astrocyte | kind of glial cell, custodial cell |