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Heme Disorders
| Term | Definition |
|---|---|
| Anemia | Lack healthy RBC |
| S/Sx of Anemia | Dizziness, Fatigue, malaise, increased heart rate, palpitations, SOB, weakness, pallor, headache, brittle nails |
| Diagnostics for Anemia | CBC, blood shape/size testing, bone marrow biopsy |
| Treatment for Anemia | Iron, vitamins, blood transfusion, medication, folic acid |
| Causes of Anemia | Iron deficiency, vitamin deficiency, anemia inflammation, aplastic anemia, bone marrow disease, hemolytic and sickle cell disease |
| Assessment for Anemia | Physical exam, past medical history, CBC, bone marrow biopsy, blood shape/ size testing |
| Most affected in Anemia | Malnourished |
| Sickle Cell Anemia | misshaped RBC |
| S/Sx of Sickle Cell Anemia | Pain in joints, dizziness, fatigue, Low O2, malaise, infections, delayed growth |
| Diagnostics for Sickle Cell Anemia | Blood tests check for Hemoglobin S, prenatal amniocentesis |
| Treatment for Sickle Cell Anemia | Bone marrow transplant, antibiotics, pain management, Hydroxyurea |
| Causes of Sickle Cell Anemia | Gene mutation in hemoglobin- inherited |
| Extra/ most affected for | One parent= trait Both parents= sickle cell |
| Assessments for Sickle Cell Anemia | Physical exam, blood tests check for hemoglobin S, prenatal amniocentesis |
| Von Willebrandt's Disease | Bleeding disorder |
| S/sx of Von Willebrandt's disease | recurrent/ prolonged nose bleeds, bleeding gums, increased menstrual flow, excessive bleeding from cuts, bruising |
| Diagnostic tests for Von Willebrandt's Disease | Von W factor antigen test, factor activity, clotting activity, factor multimers |
| Treatment for Von Willebrandt's Disease | Desmopressin, replacement therapies, oral contraceptives, clot stabilizing medications, drugs applied to cuts. |
| Causes of Von Willebrandt's Disease | Inherited abnormal gene, low levels of clotting in the blood |
| Extra/ most Affected | Autosomal dominant |
| Assessments for Von Willibrandt's Disease | Physical exam, Von W factor, clotting activity |
| Hemophilia | Bleeding disorder |
| S/sx of Hemophilia | Large deep bruises, joint pain, swelling, unexplained bleeding, blood in urine or stool, nose bleeds, unexplained irritability |
| Diagnostics for Hemophilia | blood tests |
| Treatment for Hemophilia | Desmopressin, clot preserving medication, fibrin sealants, Physical therapy, vaccinations, first aid for cuts |
| Causes of hemophilia | Lack sufficient blood clotting proteins |
| Extra/ Most affected | Occurs mostly in males. faulty gene on the X chromosome, genetics, inherited |
| Assessment for Hemophilia | Physical exam, blood tests |
Created by:
Sonimarie
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