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CH 16 Adaptive Immun

Ch 16 Adaptive Immunity

CLONAL SELECTION The development of specific B and T cells against a specific antigen.
Adaptive Immunity A vertebrate’s ability to recognize and then mount a defense against specific invaders and their products.
ANTIBODIES Proteins that are made in response to an antigen.
ANTIBODY DEPENDENT CELL MEDIATED CYTOTOXICITY The killing of antibody-coated cells by natural killer cells and leucocytes.
ANTIBODY TITER This is a reflection of the antibody-mediated humoral response and determines the relative amount of antibody in the serum.
ANTIGEN Any substance that causes antibody formation and reacts only with its specific antibody.
ANTIGEN PRESENTING CELLS These cells display a single antigen to T cells.
ANTISERUM Blood-derived fluids containing antibodies.
ARTIFICIALLY ACQUIRED ACTIVE This type of immunity results from vaccination.
ARTIFICIALLY ACQUIRED PASSIVE This type of immunity involves the transfer of preformed antibodies by injection
Autoantigens Self-antigens
B CELLS These cells manufacture specific antibodies.
CELLULAR IMMUNITY Immune response mediated by T cells.
CHEMOKINE A cytokine that induces, by chemotaxis, the migration of leukocytes into infected areas.
CYTOTOXIC T LYMPHOCYTE A specialized T cell that destroys infected cells presenting antigens.
Endogenous antigens Produced when protozoa, fungi, bacteria, and viruses reproduce inside a body’s cells.
EPITOPES Antigenic determinants.
Exogenous antigens Include toxins and other secretions and components of microbial cell walls, membranes, flagella, and pili.
GAMMA GLOBULINS Immune serum globulins.
Helper T cells These cells help to regulate the activity of B cells and cytotoxic T cells during an immune response.
HUMORAL IMMUNITY Immune response mediated by B cells.
IGA This immunoglobulin is found on mucosal surfaces.
IGD This immunoglobulin is present on the surface of B cells.
IGE This immunoglobulin is involved in allergic reactions.
IGG This is the most abundant antibody in the serum.
IGM This immunoglobulin is the first antibody produced in response to the initial infection.
IMMUNOGLOBULINS Another name for antibodies.
INFLAMMATION A host response to tissue damage characterized by redness, pain, heat and swelling.
INNATE RESISTANCE The resistance of an individual to diseases that affect other species and other individuals of the same species.
Lymph A colorless, watery liquid similar in composition to blood plasma.
Major Histocompatibility Complex A cluster of genes which codes for the major histocompatibility antigens.
MONOCLONAL ANTIBODY A specific antibody produced in vitro by a clone of B cells hybridized with cancerous cells.
MONOMER The simplest molecular structure of a bivalent antibody.
NATURAL KILLER CELL A lymphoid cell that destroys tumor cells and virus-infected cells.
NATURALLY ACQUIRED ACTIVE This type of immunity can be obtained by exposure to antigen during daily life.
NATURALLY ACQUIRED PASSIVE This type of immunity results from the natural transfer of antibodies from a mother to her infant.
Regulatory T cells Previously known as suppressor T cells, also interact with other immune cells and produce different cytokines than helper T cells.
T CELL A type of lymphocyte that is responsible for cell-mediated immunity
Primary Response The slow and limited immune response to a first encounter with an unfamiliar antigen
Created by: drmicro
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