Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


Molecular Bio: DNA Replication

DNA poly reads in which direction? RNA poly? Both read 3'-->5' (create strand 5'-->3')
What are the 2 main differences between DNA synthesis (rep) and RNA synthesis (trx)? RNA synthesis requires NO PRIMER, and has NO CORRECTION of mismatched pairs (low fidelity)
Which enzyme corrects mismatched pairs in DNA synthesis? What type of exonuclease activity is it? DNA poly III corrects mismatches (same enzyme doing the synthesis). It is 3'-->5' exonuclease.
RNA Reverse Transcriptase requires RNA Primer. True or False? True, because RNA Reverse Transcriptase is essentially a DNA Poly.
Which enzyme synthesizes leading strand in prokaryotes? Lagging strands (Okazaki fragments)? Both are done by DNA Poly III
Which enzyme REMOVES RNA Primer in Prokaryote DNA synthesis? What type of exonuclease is it? DNA Poly I, it is 5'-->3' exonuclease
Which enzyme REPLACES RNA Primer? DNA Poly I
What binds the Okazaki fragments? DNA Ligase (requires NAD)
What removes positive supercoils (give 2 names for the enzyme)? DNA Topoisomerase II (a.k.a. Gyrase)
What unwinds the DNA? Helicase. Stabilized by SSBs
3 enzymatic steps of Thymine Dimer removal Excision endonuclease-->DNA poly-->DNA Ligaes
Loss of mismatched bp removal leads to what syndrome? HNPCC (aka "Lynch Syndrome")
p53 guards the progression from which phase of the cell cycle? G1-->S
Name 2 gene mutations/inactivations that affect p53 activity, and name the associated disease? ATM gene -->Ataxia Telangectasia BRCA-1 -->breast,prostate,ovary BRCA-2 -->breast
Created by: jsad