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Respiratory Drugs 35

Chapter 35 Respiratory Drugs Lilley

QuestionAnswer
Histamine 1 Mediate smooth muscle contraction and dialation of capillaries.RESPIRATORY
Histamine 2 Mediate the acceleration of the heart rate and gastric acid secreation.GI
Histamine H2 Antagonists
Antihistamines-Fof motion sickness Give 30 min before motion
Antihistimines-ACTION Block histamine receptors
Antihistimines-USES Prevent and treat allergies and allergic reaction,decreases itching,cold
Side Effects Drowiness,dysrhythmias,dry mouth and hypotention
H1 Antagonist-Antihystamines, Drugs such as: Diphenhydramine(benadryl),chlorpheniramine,and fexofenadine.
Antitussives Dextromethorphan,benzonatate is an non opioid.
Antitussives-USES Reduces cough in non-productive cough
Side Effects Drowsiness,GI upset & Constipation
Expectorants-ActionROBITUSSIN,MUCINEX Decrease thickness of sputum for a productive cough
Expectorants-USES Decreases viscosity(thickness)and promotes more productive cough
Expectorants-SIDE EFFECTS Nausea,Vomiting,GI upset
Bronchodilators-ALBUTEROL,TERBUTALINE,SALMETEROL Relax the smooth muscles in the bronchioles,producing dilation.
Bronchodilators-USES Asma,bronchitis and emphysema and control of chronic airway problems
Bronchodilators-SIDE EFFECTS TAKE PULSE BEFORE GIVEN Anxiety and Tremors,Angina,Tachycardia and Headache,Increase Pulse
Anticholinergics COPD-There are two drugs that are used(ipratropium andtiotropium)
Antihistamine that does not cause drowisness? loratadine(Claritin)
Which drugs are considered first-line drugs for the treatment of nasal congestion? Decongestants such as Naphazoline
Antittussive primary action Stop the cough reflex when the cough is non-productive
Diphenhydramine(Sleep) Causes a hangover effect during the day after taking it.
Antihistamines are best tolerated when? Taken with meals
The main adverse effect of antihistamine is? Drowsiness
Antihistamines can cause? Dry Mouth
Beta Agonist A large group of drugs used in acute of asmatic attack.(Albuteral,epinephrine)
Excessive amonts of histamine can lead to anaphylaxis and severe allergic symptoms such as Constriction of smooth muscle especially in stomach,lungs.^ body secretions,Vasodialation
H2 Antagonist or Beta Blockers include such drugs as: cimetidine,rantindine,famotidine,and nazitatidine-they act on GI system
Histamine is a major inflammatory mediator of many alergic disorders such as: Allergic rhinitis(inflamation of nasal passage)hayfever,mold,dust allergies,anaphylaxis,angiodema(swelling of skin)
Antitussive Drugs-opioid-hydrocodone and codine Side Effects-sedation,nausea,vomiting,lightheadness,constipation.
Antitussive non-opioid Benzonatate-dizzy,headache,sedation,nauseadextromethorphan-dizzy,drowsy,nausea
Decongestants:Adrenegics(sympathomimetics)Largest group of anticholinergics(parasymphatholytics)
Anticholinerigics Block the ACh receptors to prevent bronconstriction.this causes airway dialation
Anticholinergics-Contraindications Allergy to atropine or to soy lecithin found in some inhalation formulations.(peanut iols,soybean and other beans.
Anticholinergics Side Effects dry mouth or throat,nasal congestion,heart palputations
Antileukotrienes A new class of asma medication(leukotriene receptor antagonists(LTRs)
Antileukotrienes-SINGULAR-Action Blocks Inflammatory process of asma
SIDE EFFECTS OF SINGULAR Headache,dypepsi,nausea,dizziness,insomia
Corticosteroids-Anti-Imflamatory-Decreases Inflamation. Prednisone,Cortisone,Dexamethasone
Corticosteriods-Side EFFECTS Peptic ulcer,GI Bleeding,hyperglycemia,delayed wound healing,Cushings Syndrome
WARNINGS OF CORTICOSTEROIDS Check fluid balance,potassium and glucose levels
Mast Cell Stabilizer-Rarely Used cromolyn and nedocromil-they prevent the release inflammitory mediator such as histamine
Created by: Angela Lacey
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