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Pharm2 Chapter 38
| Question | Answer |
|---|---|
| These antibiotics are bactericidal, prevent protein synthesis, kills mostly gram negative, have poor oral absorption, so therefore has no PO form | Aminoglycosides |
| This is a Aminoglycoside, which is the only one that can be given orally, because it decontaminates the GI tract before a surgical procedure | Neomycin |
| Aminoglycosides can cause serious toxicities such as | Nephrotoxicity ( renal damage), Ototoxicity (auditory impairment and vestibular {eighth cranial nerve}) |
| What are some other common side effects of aminoglycosides | Headache, paresthesia, fever, superinfections, vertigo, skin rash, and dizziness |
| This antibiotic has an excellent oral absorption, and is most effective against gram negative organisms | Fluoroquinolones |
| What is the most commonly used Fluoroquinolones | Levofloxacin (Levaquin) |
| What are Fluoroquinolone indications | LRI, bone and joint infection, infectious diarrhea, UTI, skin infections, STD’s, and anthrax |
| Fluoroquinolones may cause what side effect | Thrush |
| If taken with Fluoroquinolones, absorption is reduced | Antacids |
| What is the most common side effect with Levofloxacin (Levaquin) | Photosensitivity |