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Pharm2 Chapter 41

QuestionAnswer
1. What is mycosis a. An infection caused by pathologic fungus
2. Molds are a. Multicellular
3. Yeasts are a. Single celled organisms
4. Yeasts produce how a. By budding
5. Molds are characterized by what a. Long, branching filaments called hyphae
6. The most commonly used antifungal drug is by what method a. Topical
7. Some examples of topical antifungal drugs are a. Clotrimazole (lotrimin), miconazole (monistat), nystatin
8. Fungi are difficult to treat because what reason a. Chemicals that kill fungi are not tolerate by humans
9. What is the oldest antifungal drug a. Amphotericin B
10. A major group of antifungal drug that includes: ketoconazole, miconazole, and clotrimazole a. Imidazoles
11. These require external carbon source a. Fungi
12. Another major group including: amphotericin b and nystatin is called what a. Polyenes
13. When giving an infusion of amp b, what s/e should you monitor for a. Chills, fever, and malaise
14. The drug of choice for systemic fungal infections is a. Amp b
15. 2 drugs that are used systemically are a. Amp b and fluconazole (diflucan)
16. s/e of amp b include a. Renal toxicity, neurotoxicity- seizures and praesthesias
17. What pretreatment may reduce the severity of infusion related reactions a. Antipyretic antihistamine and antiemetics
18. When using antifungals you should obtain what a. Baseline VS, CBC, liver function studies and ECG
19. If giving amp b IV, you should use what a. The most distal vein possible
20. Nystatin suspension, taken orally should be a. Swished in the mouth thoroughly as long as possible before swallowing
21. A problem of most concern in pts about to receive antifungal meds are a. Those with hepatic disease
22. A common underlying source of drug interactions with an antifungal are a. Cytochrome P-450 enzyme system
23. When taking griseofulvin, you should look for what potential s/e a. Blood dyscrasis
Created by: cspearsall
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